ReviewLocal and regional anesthesia2018
Frailty and anesthesia - risks during and post-surgery.
Review in Local and regional anesthesia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04056871 (Comparing the Association of Different Frailty Scores to the Incidence of Post-operative Delirium and Cognitive Dysfunction), which is not on this map. Cited by 39 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparing the Association of Different Frailty Scores to the Incidence of Post-operative Delirium and Cognitive Dysfunction
Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Association between frailty and postoperative delirium after transcatheter aortic valve replacement: a meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Preoperative visit-care for transcatheter aortic valve replacement: a review.BMC cardiovascular disorders · 2024Pooled it
- Multicomponent perioperative interventions to improve outcomes for frail patients: a systematic review.BMC geriatrics · 2024Pooled it
- Efficacy and safety of ciprofol for general anesthesia induction in female patients with frailty: a prospective randomized controlled trial.BMC anesthesiology · 2024Trial
- Individualizing Perioperative Analgesia: Patient-Specific Determinants of Postoperative Pain and Opioid-Related Outcomes.Medicina (Kaunas, Lithuania) · 2026Review
- Reduced NK cell frequency in older patients with evolving fractures is linked to a distinct inflammatory cytokine profile.Immunity & ageing : I & A · 2026Article
- A predictive tool incorporating frailty scores for perioperative risk assessment in patients with spinal metastasis: a national retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Exploring the Impact of Anesthesia on Postoperative Frailty Trajectories in Older Adults.World journal of surgery · 2026Article
- Awake Percutaneous Cervical Cordotomy in Patients With Cancer: A Technical Report.Pain practice : the official journal of World Institute of Pain · 2026Article
- Prevalence of Malnutrition, Frailty, and Cachexia Across Different Cancer Subtypes: Distribution by Age (<65 and ≥65).Journal of clinical medicine · 2026Article
- Observational
- A hybrid model of ureteral stent change - ambulatory cystoscopy suite under local anesthesia versus operating room under general or monitored anesthesia.World journal of urology · 2026Article
- Incidence and Risk Factors of Postoperative Complications in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy: A Retrospective Study.Turkish journal of anaesthesiology and reanimation · 2025Article
- How are cognitive functions affected by different sedation methods in geriatric endoscopic retrograde cholangiopancreatography patients?BMC anesthesiology · 2025Observational
- The Preoperative Waiting Time on Long-Term Survival Following Elderly Hip Fracture Surgery.Geriatrics (Basel, Switzerland) · 2025Article
- The prognostic role of frailty on outcomes following meningioma resection in the elderly: a matched analysis employing baseline functional status.Acta neurochirurgica · 2025Article
- Effect of preoperative rapamycin supplementation on perioperative clinical frailty and cognitive performance in a murine model undergoing anesthesia and surgery.Scientific reports · 2025Article
- Key issues in frailty and postoperative opioid consumption.Journal of anesthesia · 2025Article
- Multimodal analgesia in cardiac surgery: Impact on postoperative medication consumption and cognitive function.World journal of cardiology · 2025Article
- Strengthening Patient Education on Anesthesia Risks by Overcoming Existing Challenges.Annals of cardiac anaesthesia · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty is a state of decreased physiologic reserve and resistance to stressors. Its prevalence increases with age and is estimated to be 26% in those aged above 85 years. As the population ages, frailty will be increasingly seen in surgical patients receiving anesthesia. Here, we evaluate the instruments which have been developed and validated for measuring frailty in surgical patients and summarize frailty tools used in 110 studies linking frailty status with adverse outcomes post-surgery. Frail older people are vulnerable to geriatric syndromes, and complications such as postoperative cognitive dysfunction and delirium are explored. This review also considers how frailty, with its decline of organ function, affects the metabolism of anesthetic agents and may influence the choice of anesthetic technique in an older person. Optimal perioperative care includes the identification of frailty, a multisystem and multidisciplinary evaluation preoperatively, and discussion of treatment goals and expectations. We conclude with an overview of the emerging evidence that Comprehensive Geriatric Assessment can improve postoperative outcomes and a discussion of the models of care that have been developed to improve preoperative assessment and enhance the postoperative recovery of older surgical patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.