ArticlePediatric research2018
Catch-up growth, metabolic, and cardiovascular risk in post-institutionalized Romanian adolescents.
Article in Pediatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 34 citations in OpenAlex.
- Physical and neurophysiological maturation associated with ADHD among previously institutionalized children: a randomized controlled trial.Journal of child psychology and psychiatry, and allied disciplines · 2025Trial
- Early-life adversity before age 5 is associated with reduced cardiometabolic health characterized by increased arterial stiffness and inflammation in adolescence.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- Anthropometry After Prematurity and Foetal Growth Restriction in Childhood and Adolescence.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Growth Trajectories During Early Childhood and Ocular Development in High-Risk Infants.Investigative ophthalmology & visual science · 2026Article
- Effect of chorioamnionitis on postnatal growth in very preterm infants: a population-based study in Japan.Archives of gynecology and obstetrics · 2025Article
- The Impact of Rapid Growth After Retardation at the First 1000 Days of Life (FDLs) on the Risk of Noncommunicable Diseases in Indonesian Adolescence.International journal of pediatrics · 2025Article
- Lingering Effects of Early Institutional Rearing and Cytomegalovirus Infection on the Natural Killer Cell Repertoire of Adopted Adolescents.Biomolecules · 2024Article
- Early Life Stress Is Associated with Alterations in Lymphocyte Subsets Independent of Increased Inflammation in Adolescents.Biomolecules · 2024Article
- Review
- Sexually dimorphic impact of preconceptional and gestational exposure to a real-life environmental chemical mixture (biosolids) on offspring growth dynamics and puberty in sheep.Environmental toxicology and pharmacology · 2023Article
- [Association between different growth patterns and metabolic syndrome in children and adolescents aged 7 to 17 years].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- A Whey-Based Diet Can Ameliorate the Effects of LPS-Induced Growth Attenuation in Young Rats.Nutrients · 2023Article
- The association of gestational age and birthweight with blood pressure, cardiac structure, and function in 4 years old: a prospective birth cohort study.BMC medicine · 2023Article
- Early-life stress and current stress predict BMI and height growth trajectories in puberty.Developmental psychobiology · 2022Article
- Sex Differences at Early Old Stage in Glycolipid Metabolism and Fatty Liver in Offspring Prenatally Exposed to Chinese Great Famine.Frontiers in nutrition · 2022Article
- Catch-up growth in juvenile rats, fat expansion, and dysregulation of visceral adipose tissue.Pediatric research · 2022Article
- What was learned from studying the effects of early institutional deprivation.Pharmacology, biochemistry, and behavior · 2021Review
- Implication of RAS in Postnatal Cardiac Remodeling, Fibrosis and Dysfunction Induced by Fetal Undernutrition.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021Article
- Low Birthweight as a Risk Factor for Non-communicable Diseases in Adults.Frontiers in medicine · 2021Review
- Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundReduced prenatal growth followed by rapid postnatal weight gain are risk factors for developing metabolic and cardiovascular disease. Children reared in institutions experience a similar pattern of growth restriction followed by catch-up growth after removal. We explored whether patterns of catch-up growth affect metabolic and cardiovascular outcomes in previously institutionalized adolescents.
methodA longitudinal study of institutionalized infants randomized to care as usual (n = 68) or foster care intervention (n = 68), and never institutionalized controls (n = 127). Body mass index (BMI) was measured at baseline (20 months), 30, 42 months, and ages 8, 12, 16. At age 16, metabolic and pro-inflammatory markers were derived from blood samples.
resultsFour BMI trajectories were derived (i.e., average-stable, low-stable, elevated, and accelerated). The accelerated trajectory was comprised predominately of children randomized to foster care, who also exhibited higher levels of glycosylated hemoglobin and C-reactive protein than the other three trajectories. Also, children placed in foster care at younger ages were more likely to be on the accelerated rather than the average-stable trajectory.
conclusionsAlthough catch-up growth is viewed as a positive improvement among post-institutionalized children, rapid/continuous increases in body size pose a health concern. Attention should be given to monitoring weight gain, diet, and physical activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.