Evidence map›Paper›PMID 30323324›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2018

Preserved speed of processing and memory in infants with a history of moderate neonatal encephalopathy treated with therapeutic hypothermia.

Elizabeth P Zorn, Lei Zhang, Kristin Sandness, Neely Miller, Tracy Riggins, Michael K Georgieff, Katie M Pfister

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elizabeth P ZornDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, USA. zornx011@umn.edu.ORCID http://orcid.org/0000-0003-4271-811X
Lei ZhangBiostatistical Design and Analysis Center, University of Minnesota, Minneapolis, MN, USA.
Kristin SandnessCenter for Neurobehavioral Development, University of Minnesota, Minneapolis, MN, USA.
Neely MillerCenter for Neurobehavioral Development, University of Minnesota, Minneapolis, MN, USA.
Tracy RigginsDepartment of Psychology, University of Maryland, College Park, MD, USA.
Michael K GeorgieffDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
Katie M PfisterDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, USA.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences (NCATS) UL1TR000114
6 · The paper itself

Abstract

objectiveSurvivors of neonatal encephalopathy (NE) are at risk for impaired cognition. The objective of this study was to assess speed of processing (SOP) and memory in infants with moderate NE. STUDY

designSample consisted of 17 infants with NE and 23 healthy controls. Visual-evoked potentials (VEP) were assessed at 8 months to assess SOP. Memory was assessed at 12 months using elicited imitation (EI). Memory and SOP had previously been assessed in this cohort in the newborn period.

resultsInfants with NE had similar SOP and EI performance as controls. Newborn SOP correlated with 8-month SOP in infants with NE, however, neonatal ERP memory measures were not correlated with EI performance at 12 months.

conclusionsInfants with moderate NE treated with TH show preserved memory and SOP through 12 months. Early behavioral and electrophysiologic assessments of memory and SOP provide insight into developing cognitive functions in this risk group.

Indexed as

CognitionHypothermia, InducedMemoryBrain DiseasesCase-Control StudiesChild DevelopmentEvoked PotentialsFemaleHumansInfantInfant, NewbornLinear ModelsMaleNeurologic ExaminationPsychomotor Performance

Identifiers

PMID30323324

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.