Evidence map›Paper›PMID 30323175›Full record

ArticleEuropean journal of clinical nutrition2019

Cruciferous vegetables and colorectal cancer risk: a hospital-based matched case-control study in Northeast China.

Wanxia Fang, Xiujuan Qu, Jing Shi, Heming Li, Xiaoyu Guo, Xin Wu, Yunpeng Liu, Zhi Li

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Article in European journal of clinical nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wanxia FangDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang, 110001, China.
Xiujuan QuDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang, 110001, China.
Jing ShiDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang, 110001, China.
Heming LiDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang, 110001, China.
Xiaoyu GuoDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang, 110001, China.
Xin WuDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang, 110001, China.
Yunpeng LiuDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang, 110001, China. cmuliuyunpeng@hotmail.com.
Zhi LiDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang, 110001, China. zli@cmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesConflicting results have been reported on the association of cruciferous vegetable intake and colorectal cancer risk. This study aimed to clarify the relationship of cruciferous vegetables and colorectal cancer among individuals in Northeast China, where large amounts of cruciferous vegetables are consumed habitually. SUBJECTS/

methodsWe conducted a hospital-based case-control study in the First Hospital of China Medical University, the Shengjing Hospital of China Medical University and the First Hospital of Dalian Medical University from 2009 to 2011. Patients in the study were matched individually by age, gender, and city of residence. The study ultimately included 833 case-control pairs. A structured questionnaire was applied to collect data on general characteristics, dietary habits, and selected dietary intake. Differences between cases and controls were ascertained with the chi-square test or the Mann-Whitney U test. Unconditional logistic regression was employed to compute odds ratios (ORs) and 95% confidence intervals (CIs). Stratified analyses were conducted by gender.

resultsIn the total study cohort, no significant association was found between total cruciferous vegetable intake and colorectal cancer risk. The adjusted OR for the highest versus the lowest intake was 0.83 (95% CI: 0.59-1.18). In stratification analyses by gender, reduced colorectal cancer risk was related to higher consumption of total cruciferous vegetables in women but not in men. Significant inverse correlations were found in analyses of individual cruciferous vegetables, including greens (OR = 0.47; 95% CI: 0.32-0.68), cabbage (OR = 0.61; 95% CI: 0.44-0.86), and cauliflower (OR = 0.66; 95% CI: 0.48-0.92).

conclusionsNo significant association was found between total cruciferous vegetable intake and colorectal cancer risk. However, specific types of cruciferous vegetables might have protective roles against colorectal cancer.

Indexed as

VegetablesAdultCase-Control StudiesChinaCohort StudiesColorectal NeoplasmsDietFemaleHumansMaleMiddle AgedRiskSurveys and Questionnaires

Identifiers

PMID30323175

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.