Evidence map›Paper›PMID 30323015›Full record

ReviewCold Spring Harbor perspectives in medicine2019

Active Biomechanics of Sensory Hair Bundles.

Dolores Bozovic

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Whistling While it Works: Spontaneous Otoacoustic Emissions and the Cochlear Amplifier.Journal of the Association for Research in Otolaryngology : JARO · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Dolores BozovicDepartment of Physics and Astronomy, University of California, Los Angeles, California 90095-1547.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the detection of sound, hair bundles perform a crucial step by responding to mechanical deflections and converting them into changes in electrical potential that subsequently lead to the release of neurotransmitter. The sensory hair bundle response is characterized by an essential nonlinearity and an energy-consuming amplification of the incoming sound. The active response has been shown to enhance the hair bundle's sensitivity and frequency selectivity of detection. The biological phenomena shown by the bundle have been extensively studied in vitro, allowing comparisons to behaviors observed in vivo. The experimental observations have been well explained by numerical simulations, which describe the cellular mechanisms operant within the bundle, as well as by more sparse theoretical models, based on dynamical systems theory.

Indexed as

AnimalsCompressive StrengthHair Cells, AuditoryHearingHumansIn Vitro TechniquesMechanotransduction, CellularModels, BiologicalMovementNonlinear DynamicsOscillometry

Identifiers

PMID30323015
PMCPMC6824401

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.