Evidence map›Paper›PMID 30322972›Full record

ArticleThe Journal of cell biology2018

mRNP architecture in translating and stress conditions reveals an ordered pathway of mRNP compaction.

Anthony Khong, Roy Parker

Abstract read
In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed.

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  20. Review

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anthony KhongHoward Hughes Medical Institute, University of Colorado, Boulder, CO.ORCID 0000-0002-4293-8879
Roy ParkerHoward Hughes Medical Institute, University of Colorado, Boulder, CO roy.parker@colorado.edu.ORCID 0000-0002-8412-4152

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Stress granules (SGs) are transient membraneless organelles of nontranslating mRNA-protein complexes (mRNPs) that form during stress. In this study, we used multiple single-molecule FISH probes for particular mRNAs to examine their SG recruitment and spatial organization. Ribosome runoff is required for SG entry, as long open reading frame (ORF) mRNAs are delayed in SG accumulation, indicating that the SG transcriptome changes over time. Moreover, mRNAs are

Indexed as

3' Untranslated RegionsOpen Reading FramesCytoplasmic GranulesHeLa CellsHumansModels, BiologicalRibonucleoproteinsRibosomes3' Untranslated Regionsmessenger ribonucleoproteinRibonucleoproteins

Identifiers

PMID30322972
PMCPMC6279387

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.