ArticleProceedings of the National Academy of Sciences of the United States of America2018
Prevalent reliance of bacterioplankton on exogenous vitamin B1 and precursor availability.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 70 citations in OpenAlex.
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- Functional complementarity between vitamin B1 and B12 metabolisms shapes seasonal marine microbial communities.The ISME journal · 2026Article
- Pronounced seasonal dynamics in transcription of vitamin B1 acquisition strategies diverge among Baltic Sea bacterioplankton.Environmental microbiome · 2025Article
- Harmful algal bloom speciesmBio · 2025Article
- Vitamin auxotrophies shape microbial community assembly on model marine particles.The ISME journal · 2025Article
- Astaxanthin and thiamine dynamics in the copepod Temora longicornis in response to ultraviolet radiation exposure.PloS one · 2025Article
- Bacimethrin, an allelopathic vitamin B1 antagonist, is linked with microbial gene expression patterns in a hypereutrophic watershed.PloS one · 2025Article
- Dark ocean archaeal and bacterial chemoautotrophs drive vitamin B1 production in oxygen minimum zones.ISME communications · 2025Article
- Whole cell affinity for 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) in the marine bacterium Candidatus Pelagibacter st. HTCC7211 explains marine dissolved HMP concentrations.Environmental microbiology reports · 2024Article
- Genome-scale community modelling reveals conserved metabolic cross-feedings in epipelagic bacterioplankton communities.Nature communications · 2024Article
- Connecting thiamine availability to the microbial community composition in Chinook salmon spawning habitats of the Sacramento River basin.Applied and environmental microbiology · 2024Article
- Thiamin (vitamin B1, thiamine) transfer in the aquatic food web from lower to higher trophic levels.PloS one · 2024Article
- New chemical and microbial perspectives on vitamin B1 and vitamer dynamics of a coastal system.ISME communications · 2024Article
- Taxonomic and environmental distribution of bacterial amino acid auxotrophies.Nature communications · 2023Article
- Article
- Distribution, abundance, and ecogenomics of themSystems · 2023Article
- Multiyear analysis uncovers coordinated seasonality in stocks and composition of the planktonic food web in the Baltic Sea proper.Scientific reports · 2023Article
- Genetic basis of thiaminase I activity in a vertebrate, zebrafish Danio rerio.Scientific reports · 2023Article
- The overlooked role of a biotin precursor for marine bacteria - desthiobiotin as an escape route for biotin auxotrophy.The ISME journal · 2022Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin B1 (B1 herein) is a vital enzyme cofactor required by virtually all cells, including bacterioplankton, which strongly influence aquatic biogeochemistry and productivity and modulate climate on Earth. Intriguingly, bacterioplankton can be de novo B1 synthesizers or B1 auxotrophs, which cannot synthesize B1 de novo and require exogenous B1 or B1 precursors to survive. Recent isolate-based work suggests select abundant bacterioplankton are B1 auxotrophs, but direct evidence of B1 auxotrophy among natural communities is scant. In addition, it is entirely unknown if bulk bacterioplankton growth is ever B1-limited. We show by surveying for B1-related genes in estuarine, marine, and freshwater metagenomes and metagenome-assembled genomes (MAGs) that most naturally occurring bacterioplankton are B1 auxotrophs. Pyrimidine B1-auxotrophic bacterioplankton numerically dominated metagenomes, but multiple other B1-auxotrophic types and distinct uptake and B1-salvaging strategies were also identified, including dual (pyrimidine and thiazole) and intact B1 auxotrophs that have received little prior consideration. Time-series metagenomes from the Baltic Sea revealed pronounced shifts in the prevalence of multiple B1-auxotrophic types and in the B1-uptake and B1-salvaging strategies over time. Complementarily, we documented B1/precursor limitation of bacterioplankton production in three of five nutrient-amendment experiments at the same time-series station, specifically when intact B1 concentrations were ≤3.7 pM, based on bioassays with a genetically engineered
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