Evidence map›Paper›PMID 30322913›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Frequent monoallelic or skewed expression for developmental genes in CNS-derived cells and evidence for balancing selection.

Sergio Branciamore, Zuzana Valo, Min Li, Jinhui Wang, Arthur D Riggs, Judith Singer-Sam

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sergio BranciamoreDiabetes and Metabolism Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA 91010; ariggs@coh.org SBranciamore@coh.org jsam@coh.org.
Zuzana ValoDiabetes and Metabolism Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA 91010.
Min LiDivision of Biostatistics, City of Hope Comprehensive Cancer Center, Duarte, CA 91010.
Jinhui WangIntegrative Genomics Core, City of Hope Comprehensive Cancer Center, Duarte, CA 91010.
Arthur D RiggsDiabetes and Metabolism Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA 91010; ariggs@coh.org SBranciamore@coh.org jsam@coh.org.
Judith Singer-SamDiabetes and Metabolism Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA 91010; ariggs@coh.org SBranciamore@coh.org jsam@coh.org.
City of Hope · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI STANLEY R. HAMILTON · 1985 to 2026
$86.3M
NCI NIH HHS P30 CA033572
6 · The paper itself

Abstract

Cellular mosaicism due to monoallelic autosomal expression (MAE), with cell selection during development, is becoming increasingly recognized as prevalent in mammals, leading to interest in understanding its extent and mechanism(s). We report here use of clonal cell lines derived from the CNS of adult female [Formula: see text] hybrid (C57BL/6 X JF1) mice to characterize MAE as neural stem cells (

Indexed as

AllelesAnimalsAstrocytesCell DifferentiationCentral Nervous SystemFemaleGene Expression Regulation, DevelopmentalGenes, DevelopmentalMiceMice, Inbred C57BLNeural Stem CellsPromoter Regions, GeneticSelection, GeneticdifferentiationevolutionGstm5overdominanceschizophrenia

Identifiers

PMID30322913
PMCPMC6217436
OpenAlexW2896537917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.