Evidence map›Paper›PMID 30322888›Full record

ArticleLearning & memory (Cold Spring Harbor, N.Y.)2018

A principled method to identify individual differences and behavioral shifts in signaled active avoidance.

Angelos-Miltiadis Krypotos, Justin M Moscarello, Robert M Sears, Joseph E LeDoux, Isaac Galatzer-Levy

Abstract read
In one paragraph

Article in Learning & memory (Cold Spring Harbor, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angelos-Miltiadis KrypotosDepartment of Clinical Psychology, Utrecht University, Utrecht 3584 CS, The Netherlands.ORCID 0000-0001-9704-6520
Justin M MoscarelloDepartment of Psychological and Brain Sciences, Texas A&M University, College Station, Texas 4235 TAMU, USA.
Robert M SearsCenter for Neural Science, New York University, New York, New York 10003, USA.
Joseph E LeDouxCenter for Neural Science, New York University, New York, New York 10003, USA.
Isaac Galatzer-LevyDepartment of Psychiatry, New York University Langone Medical Center, New York, New York 10016, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Signaled active avoidance (SigAA) is the key experimental procedure for studying the acquisition of instrumental responses toward conditioned threat cues. Traditional analytic approaches (e.g., general linear model) often obfuscate important individual differences, although individual differences in learned responses characterize both animal and human learning data. However, individual differences models (e.g., latent growth curve modeling) typically require large samples and onerous computational methods. Here, we present an analytic methodology that enables the detection of individual differences in SigAA performance at a high accuracy, even when a single animal is included in the data set (i.e., n = 1 level). We further show an online software that enables the easy application of our method to any SigAA data set.

Indexed as

Avoidance LearningIndividualityModels, StatisticalPsychological TestsSoftwareAnimalsConditioning, PsychologicalData Interpretation, StatisticalMaleRats, Sprague-DawleyReaction TimeReproducibility of Results

Identifiers

PMID30322888
PMCPMC6191017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.