Evidence map›Paper›PMID 30322857›Full record

ArticleJournal of bacteriology2019

The Escherichia coli β-Barrel Assembly Machinery Is Sensitized to Perturbations under High Membrane Fluidity.

Kelly M Storek, Rajesh Vij, Dawei Sun, Peter A Smith, James T Koerber, Steven T Rutherford

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

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  3. A fluorescent reporter and single-turnover kinetics reveal insight into BAM complex function.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelly M StorekDepartment of Infectious Diseases, Genentech, Inc., South San Francisco, California, USA.
Rajesh VijDepartment of Antibody Engineering, Genentech, Inc., South San Francisco, California, USA.
Dawei SunDepartment of Structural Biology, Genentech, Inc., South San Francisco, California, USA.
Peter A SmithDepartment of Infectious Diseases, Genentech, Inc., South San Francisco, California, USA.
James T KoerberDepartment of Antibody Engineering, Genentech, Inc., South San Francisco, California, USA.
Steven T RutherfordDepartment of Infectious Diseases, Genentech, Inc., South San Francisco, California, USA rutherford.steven@gene.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integral β-barrel membrane proteins are folded and inserted into the Gram-negative bacterial outer membrane by the β-barrel assembly machine (BAM). This essential complex, composed of a β-barrel protein, BamA, and four lipoproteins, BamB, BamC, BamD, and BamE, resides in the outer membrane, a unique asymmetrical lipid bilayer that is difficult to recapitulate

Indexed as

Membrane FluidityProtein FoldingProtein MultimerizationAmino Acid SubstitutionBacterial Outer Membrane ProteinsDNA Mutational AnalysisEscherichia coliEscherichia coli ProteinsLipoproteinsBacterial Outer Membrane ProteinsBamA protein, E coliEscherichia coli ProteinsLipoproteinsBamABamBmembrane fluidityOMPsouter membrane

Identifiers

PMID30322857
PMCPMC6287456
OpenAlexW2897895147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.