Evidence map›Paper›PMID 30322597›Full record

ReviewNeuroimaging clinics of North America2018

Clot Pathophysiology: Why Is It Clinically Important?

Patrick A Brouwer, Waleed Brinjikji, Simon F De Meyer

Abstract readCase ReportsReview
In one paragraph

Review in Neuroimaging clinics of North America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
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  12. Review
  13. Correlation of Neutrophil to Lymphocyte Ratio with Expression of Neutrophil Extracellular Traps Within Stroke Emboli.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
    Article
  14. Article
  15. Article
  16. A Review of the Advancements in theFrontiers in medical technology · 2022
    Review
  17. Article
  18. Review
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  20. Aortic and supra-aortic arterial tortuosity and access technique: Impact on time to device deployment in stroke thrombectomy.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patrick A BrouwerNeuroradiology Department, Neurointervention Section, Karolinska University Hospital, Eugeniavägen 3, Stockholm, 171 64 Solna, Sweden. Electronic address: patrickbrouwermd@gmail.com.
Waleed BrinjikjiDepartment of Radiology, Mayo Clinic, 1216 2nd St SW, Rochester, MN 55902, USA; Department of Neurosurgery, Mayo Clinic, 1216 2nd St SW, Rochester, MN 55902, USA; Joint Department of Medical Imaging, Toronto Western Hospital, 399 Bathurst St, Toronto, ON M5T 2S8, Canada.
Simon F De MeyerLaboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, E. Sabbelaan 53, 8500 Kortrijk, Belgium.

Funding

Impact of Clot Histological and Physical Properties on Revascularization Strategies in Acute Ischaemic Stroke - Administrative SupplementR01NS105853 · NINDS · MAYO CLINIC ROCHESTER · PI BRINJIKJI, WALEED · 2018 to 2022
$2.0M
NINDS NIH HHS R01 NS105853
6 · The paper itself

Abstract

Cerebral ischemic stroke treatment may change significantly now that clots are actually physically removed from the patient using thrombectomy. This allows for an analysis of the content of the clots as well as the correlation of the imaging findings and the clot behavior and morphology. This article illustrates how the interaction of different clots varies in the clinical setting and how analysis of clot composition, as well as the search for new pharmacologic targets, can lead to a better understanding of the pathophysiology and therapy resistance, in turn providing possibilities for a better approach in the treatment.

Indexed as

AdultAgedBrain IschemiaDiagnostic ImagingFemaleHumansStrokeThrombosisYoung AdultBlood clotCerebral ischemic strokeEtiologyPathophysiologyThrombectomy

Identifiers

PMID30322597
PMCPMC6910231

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.