Evidence map›Paper›PMID 30322202›Full record

ReviewInternational journal of molecular sciences2018

The Potential of Intrinsically Magnetic Mesenchymal Stem Cells for Tissue Engineering.

Fransiscus F A Kerans, Lisa Lungaro, Asim Azfer, Donald M Salter

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Application of nanoparticles in breast cancer treatment: a systematic review.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Size tunable fabrication of magnetic alginate microparticles using flow focusing microfluidics.Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems · 2023
    Article
  9. Magnetic Nanocomposite Materials Based on FeInternational journal of molecular sciences · 2023
    Article
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Fransiscus F A KeransCentre for Genomics and Experimental Medicine, MRC IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK. s1578984@sms.ed.ac.uk.
Lisa LungaroCentre for Genomics and Experimental Medicine, MRC IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK. Lisa.Lungaro@gmail.com.
Asim AzferCentre for Genomics and Experimental Medicine, MRC IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK. aazfer@ed.ac.uk.
Donald M SalterCentre for Genomics and Experimental Medicine, MRC IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK. donald.salter@ed.ac.uk.
University of Edinburgh · GB

Funding

Medical Research Council MC_PC_14104The Indonesia Endowment Fund for Education S-4064/LPDP.3/2015
6 · The paper itself

Abstract

The magnetization of mesenchymal stem cells (MSC) has the potential to aid tissue engineering approaches by allowing tracking, targeting, and local retention of cells at the site of tissue damage. Commonly used methods for magnetizing cells include optimizing uptake and retention of superparamagnetic iron oxide nanoparticles (SPIONs). These appear to have minimal detrimental effects on the use of MSC function as assessed by in vitro assays. The cellular content of magnetic nanoparticles (MNPs) will, however, decrease with cell proliferation and the longer-term effects on MSC function are not entirely clear. An alternative approach to magnetizing MSCs involves genetic modification by transfection with one or more genes derived from

Indexed as

Genes, BacterialAnimalsCell DifferentiationCell ProliferationCell TrackingHumansMagnetic Resonance ImagingMagnetite NanoparticlesMagnetosomesMagnetospirillumMesenchymal Stem CellsTissue EngineeringTransfectionMagnetite Nanoparticlesmagnetic nanoparticlesmagnetosomesmagnetotactic bacteriamesenchymal stem cellstissue engineering

Identifiers

PMID30322202
PMCPMC6214112
OpenAlexW2897808317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.