ArticleMolecules (Basel, Switzerland)2018
Insight into the Influence of Cultivar Type, Cultivation Year, and Site on the Lignans and Related Phenolic Profiles, and the Health-Promoting Antioxidant Potential of Flax (
Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 55 citations in OpenAlex.
- Flax Lignans: From Biosynthetic Regulation to Biological Activities.International journal of molecular sciences · 2026Review
- Article
- Combining Stable Isotope Labeling and Candidate Substrate-Product Pair Networks Reveals Lignan, Oligolignol, and Chicoric Acid Biosynthesis in Flax Seedlings (Plants (Basel, Switzerland) · 2025Article
- Review
- Application of Chia and Flaxseed Meal as an Ingredient of Fermented Vegetable-Based Spreads to Design Their Nutritional Composition and Sensory Quality.Foods (Basel, Switzerland) · 2025Article
- Unveiling the Power of Flax Lignans: From Plant Biosynthesis to Human Health Benefits.Nutrients · 2024Review
- Article
- Comparison of Yield Characteristics, Chemical Composition, Lignans Content and Antioxidant Potential of Experimentally Grown Six Linseed (Linum usitatissimum L.) Cultivars.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024Article
- Exploring Major Flavonoid Phytochemicals fromInternational journal of molecular sciences · 2023Article
- Water Stress and Seed Color Interacting to Impact Seed and Oil Yield, Protein, Mucilage, and Secoisolariciresinol Diglucoside Content in Cultivated Flax (Plants (Basel, Switzerland) · 2023Article
- Phenolic Compound Profile and Antioxidant Capacity of Flax (Molecules (Basel, Switzerland) · 2023Article
- Review
- Comparative Metabolomics study of flavonoids in the pericarp of different coloured bitter gourds (Physiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- Differential Flavonoid and Other Phenolic Accumulations and Antioxidant Activities ofMolecules (Basel, Switzerland) · 2022Article
- Flavonoid Profiles and Antioxidant Potential ofAntioxidants (Basel, Switzerland) · 2022Article
- Flaxseed Ethanol Extracts' Antitumor, Antioxidant, and Anti-Inflammatory Potential.Antioxidants (Basel, Switzerland) · 2022Article
- Article
- Validation of a High-Performance Liquid Chromatography with Photodiode Array Detection Method for the Separation and Quantification of Antioxidant and Skin Anti-Aging Flavonoids fromMolecules (Basel, Switzerland) · 2022Article
- Phytochemical Diversity and Antioxidant Potential of Natural Populations ofMolecules (Basel, Switzerland) · 2022Article
- Characterization of Bioactive Phenolics and Antioxidant Capacity of Edible Bean Extracts of 50 Fabaceae Populations Grown in Thailand.Foods (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
16 authors at 3 institutions in 3 countries.
Funding
Abstract
Flaxseeds are a functional food representing, by far, the richest natural grain source of lignans, and accumulate substantial amounts of other health beneficial phenolic compounds (i.e., flavonols, hydroxycinnamic acids). This specific accumulation pattern is related to their numerous beneficial effects on human health. However, to date, little data is available concerning the relative impact of genetic and geographic parameters on the phytochemical yield and composition. Here, the major influence of the cultivar over geographic parameters on the flaxseed phytochemical accumulation yield and composition is evidenced. The importance of genetic parameters on the lignan accumulation was further confirmed by gene expression analysis monitored by RT-qPCR. The corresponding antioxidant activity of these flaxseed extracts was evaluated, both in vitro, using ferric reducing antioxidant power (FRAP), oxygen radical absorbance capacity (ORAC), and iron chelating assays, as well as in vivo, by monitoring the impact of UV-induced oxidative stress on the lipid membrane peroxidation of yeast cells. Our results, both the in vitro and in vivo studies, confirm that flaxseed extracts are an effective protector against oxidative stress. The results point out that secoisolariciresinol diglucoside, caffeic acid glucoside, and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.