Evidence map›Paper›PMID 30322167›Full record

ArticleInternational journal of molecular sciences2018

Relationship between the Regulation of Caspase-8-Mediated Apoptosis and Radioresistance in Human THP-1-Derived Macrophages.

Hironori Yoshino, Haruka Konno, Koya Ogura, Yoshiaki Sato, Ikuo Kashiwakura

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hironori YoshinoDepartment of Radiation Science, Hirosaki University Graduate School of Health Sciences, 66⁻1 Hon-cho, Hirosaki, Aomori 036-8564, Japan. hyoshino@hirosaki-u.ac.jp.
Haruka KonnoDepartment of Radiological Technology, Hirosaki University School of Health Sciences, 66⁻1 Hon-cho, Hirosaki, Aomori 036-8564, Japan. haruknn@gmail.com.
Koya OguraDepartment of Radiological Technology, Hirosaki University School of Health Sciences, 66⁻1 Hon-cho, Hirosaki, Aomori 036-8564, Japan. k.ogura.h3@gmail.com.
Yoshiaki SatoDepartment of Radiation Science, Hirosaki University Graduate School of Health Sciences, 66⁻1 Hon-cho, Hirosaki, Aomori 036-8564, Japan. h18gg205@hirosaki-u.ac.jp.
Ikuo KashiwakuraDepartment of Radiation Science, Hirosaki University Graduate School of Health Sciences, 66⁻1 Hon-cho, Hirosaki, Aomori 036-8564, Japan. ikashi@hirosaki-u.ac.jp.
Hirosaki University · JP

Funding

Hirosaki University Hirosaki University Grant for Exploratory Research by Young ScientistsJapan Society for the Promotion of Science JP15K09985Japan Society for the Promotion of Science JP18K07623
6 · The paper itself

Abstract

Radiosensitivity varies depending on the cell type; highly differentiated cells typically exhibit greater radioresistance. We recently demonstrated that human macrophages derived from THP-1 monocytic cells, which lack

Indexed as

Down-RegulationRadiation ToleranceCaspase 8Cell DifferentiationCell SurvivalDNA Breaks, Double-StrandedDNA RepairGene Expression Regulation, NeoplasticHumansMacrophagesTHP-1 CellsTumor Suppressor Protein p53CASP8 protein, humanCaspase 8TP53 protein, humanTumor Suppressor Protein p53apoptosiscaspase-8ionizing radiationmacrophagesradioresistance

Identifiers

PMID30322167
PMCPMC6214119
OpenAlexW2896037343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.