Evidence map›Paper›PMID 30322121›Full record

ArticleInternational journal of molecular sciences2018

Zerumbone, a Tropical Ginger Sesquiterpene of

Taek-In Oh, Hye-Jeong Jung, Yoon-Mi Lee, Sujin Lee, Geon-Hee Kim, Sang-Yeon Kan, Hyeji Kang, Taerim Oh, Hyun Myung Ko, Keun-Chang Kwak and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  3. Anti-Melanogenic Effects of a Polysaccharide Isolated fromInternational journal of molecular sciences · 2024
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  11. Current issues in molecular biology · 2022
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  12. Review
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  16. Review
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  19. Article
  20. Skin Pigmentation: Is the Control of Melanogenesis a Target within Reach?International journal of molecular sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Taek-In OhDepartment of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea. dk1050@kku.ac.kr.
Hye-Jeong JungDepartment of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea. hyevely@kku.ac.kr.
Yoon-Mi LeeDepartment of Food Bioscience, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea. yoonmilee@kku.ac.kr.
Sujin LeeDepartment of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea. 201341532@kku.ac.kr.
Geon-Hee KimDepartment of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea. rlarsgml4@kku.ac.kr.
Sang-Yeon KanDepartment of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea. hsb6477@kku.ac.kr.
Hyeji KangDepartment of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea. kkang@kku.ac.kr.
Taerim OhDepartment of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea. dhxofla555@kku.ac.kr.
Hyun Myung KoDepartment of Life Science, College of Science and Technology, Woosuk University, 66 Daehak-ro, Jincheon-eup, Chungcheongbuk-do 27841, Korea. greatmen00@hanmail.com.
Keun-Chang KwakDepartment of Research & Development Center, BSB korea Co., Ltd., 66 Daehak-ro, Jincheon-eup, Chungcheongbuk-do 27841, Korea. la_chang@naver.com.
Ji-Hong LimDepartment of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea. jhlim@kku.ac.kr.
Konkuk University · KRWoosuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zerumbone (ZER), an active constituent of the Zingiberaceae family, has been shown to exhibit several biological activities, such as anti-inflammatory, anti-allergic, anti-microbial, and anti-cancer; however, it has not been studied for anti-melanogenic properties. In the present study, we demonstrate that ZER and

Indexed as

alpha-MSHAnimalsCell Line, TumorGene Expression Regulation, NeoplasticHumansIntramolecular OxidoreductasesMelanomaMembrane GlycoproteinsMiceMicrophthalmia-Associated Transcription FactorMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3OxidoreductasesPhosphorylationPlant ExtractsSesquiterpenesalpha-MSHdopachrome isomeraseIntramolecular OxidoreductasesMapk1 protein, mouseMembrane GlycoproteinsMicrophthalmia-Associated Transcription FactorMitf protein, mouseMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3OxidoreductasesPlant ExtractsSesquiterpenesTyrp1 protein, mousezerumboneERK1/2melanogenesisMITFzerumboneZingiber officinale roscoe

Identifiers

PMID30322121
PMCPMC6214111
OpenAlexW2896922798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.