Evidence map›Paper›PMID 30322031›Full record

ArticleInternational journal of environmental research and public health2018

Small-Scale Variations in Urban Air Pollution Levels Are Significantly Associated with Premature Births: A Case Study in São Paulo, Brazil.

Silvia Regina Dias Medici Saldiva, Ligia Vizeu Barrozo, Clea Rodrigues Leone, Marcelo Antunes Failla, Eliana de Aquino Bonilha, Regina Tomie Ivata Bernal, Regiani Carvalho de Oliveira, Paulo Hilário Nascimento Saldiva

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Health and the Megacity: Urban Congestion, Air Pollution, and Birth Outcomes in Brazil.International journal of environmental research and public health · 2022
    Article
  3. Article
  4. Article
  5. The Use of the Internet of Things for Estimating Personal Pollution Exposure.International journal of environmental research and public health · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Silvia Regina Dias Medici SaldivaCentro de Pesquisa e Desenvolvimento para o SUS, Instituto de Saúde, Secretaria do Estado da Saúde de São Paulo, Rua Santo Antônio, 590-Bela Vista, São Paulo 01314-000, Brazil. smsaldiva@isaude.sp.gov.br.ORCID 0000-0002-0641-834X
Ligia Vizeu BarrozoDepartamento de Geografia da Faculdade de Ciências, Letras e Filosofia da Universidade de São Paulo, Cidade Universitária, Av. Prof. Luciano Gualberto-Butantã, São Paulo 05344-020, Brazil. lija@usp.br.ORCID 0000-0001-7322-6789
Clea Rodrigues LeoneDepartamento de Pediatria da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 647-Cerqueira César, São Paulo 05403-000, Brazil. clearleone@uol.com.br.
Marcelo Antunes FaillaCoordenação de Epidemiologia e Informação (CEInfo)-Secretaria Municipal da Saúde de São Paulo, R. General Jardim, 36-5º andar-Vila Buarque, São Paulo 01223-010, Brazil. marcelofailla@prefeitura.sp.gov.br.ORCID 0000-0002-9004-7309
Eliana de Aquino BonilhaCoordenação de Epidemiologia e Informação (CEInfo)-Secretaria Municipal da Saúde de São Paulo, R. General Jardim, 36-5º andar-Vila Buarque, São Paulo 01223-010, Brazil. ebonilha@prefeitura.sp.gov.br.ORCID 0000-0002-7104-636X
Regina Tomie Ivata BernalNúcleo de Pesquisas Epidemiológicas em Nutrição e Saúde da Faculdade de Saúde Pública da Universidade de São Paulo, Av. Dr. Arnaldo, 715-Cerqueira César, São Paulo 01246-000, Brazil. rbernal@usp.br.
Regiani Carvalho de OliveiraLaboratório de Poluição Ambiental do Departamento de Patologia da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Arnaldo, 455-Cerqueira César, São Paulo 01246-903, Brazil. regiani@usp.br.ORCID 0000-0003-2871-0162
Paulo Hilário Nascimento SaldivaInstituto de Estudos Avançados da Universidade de São Paulo, Rua da Praça do Relógio, 109 andar Térreo. Cidade Universitária, São Paulo 05508-050, Brazil. pepino@usp.br.
Universidade de São Paulo · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRSecretaria Municipal de Saúde · BRInstituto de Saúde · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Premature birth is the result of a complex interaction among genetic, epigenetic, behavioral, socioeconomic, and environmental factors. We evaluated the possible associations between air pollution and the incidence of prematurity in spatial clusters of high and low prevalence in the municipality of São Paulo. It is a spatial case-control study. The residential addresses of mothers with live births that occurred in 2012 and 2013 were geo-coded. A spatial scan statistical test performed to identify possible low-prevalence and high-prevalence clusters of premature births. After identifying, the spatial clusters were drawn samples of cases and controls in each cluster. Mothers were interviewed face-to-face using questionnaires. Air pollution exposure was assessed by passive tubes (NO₂ and O₃) as well as by the determination of trace elements' concentration in tree bark. Binary logistic regression models were applied to determine the significance of the risk of premature birth. Later prenatal care, urinary infection, and hypertension were individual risk factors for prematurity. Particles produced by traffic emissions (estimated by tree bark accumulation) and photochemical pollutants involved in the photochemical cycle (estimated by O₃ and NO₂ passive tubes) also exhibited significant and robust risks for premature births. The results indicate that air pollution is an independent risk factor for prematurity.

Indexed as

Air PollutantsAir PollutionBrazilCase-Control StudiesFemaleHumansIncidenceInfant, NewbornMalePregnancyPremature BirthPrevalenceRisk FactorsSpatial AnalysisUrban PopulationAir Pollutantsair monitoringair pollutionpremature birthspatial analysis

Identifiers

PMID30322031
PMCPMC6209908
OpenAlexW2896095398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.