ArticleMagnetic resonance in medicine2019
Respiratory- and cardiac motion-corrected simultaneous whole-heart PET and dual phase coronary MR angiography.
Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Molecular Imaging of Coronary Plaque Vulnerability Using 18F-Fluorocholine PET-MRI in Patients with Coronary Artery Disease: Validation with Optical Coherence Tomography.Journal of clinical medicine · 2025Article
- Low-Dose PET Imaging of Tumors in Lung and Liver Regions Using Internal Motion Estimation.Diagnostics (Basel, Switzerland) · 2021Article
- Hybrid PET/MR imaging in myocardial inflammation post-myocardial infarction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Review
- Iterative motion-compensation reconstruction ultra-short TE (iMoCo UTE) for high-resolution free-breathing pulmonary MRI.Magnetic resonance in medicine · 2020Article
- Value of simultaneous assessment of cardiac functions by PET/MRI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Respiratory- and cardiac motion-corrected simultaneous whole-heart PET and dual phase coronary MR angiography.Magnetic resonance in medicine · 2019Article
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Authors and funding
6 authors.
Funding
Abstract
purposeTo develop a framework for efficient and simultaneous acquisition of motion-compensated whole-heart coronary MR angiography (CMRA) and left ventricular function by MR and myocardial integrity by PET on a 3T PET-MR system.
methodsAn acquisition scheme based on a dual-phase CMRA sequence acquired simultaneously with cardiac PET data has been developed. The framework is integrated with a motion-corrected image reconstruction approach, so that non-rigid respiratory and cardiac deformation fields estimated from MR images are used to correct both the CMRA (respiratory motion correction for each cardiac phase) and the PET data (respiratory and cardiac motion correction). The proposed approach was tested in a cohort of 8 healthy subjects and 6 patients with coronary artery disease. Left ventricular (LV) function estimated from motion-corrected dual-phase CMRA was compared to the gold standard estimated from a stack of 2D CINE images for the healthy subjects. Relative increase of signal in motion-corrected PET images compared to uncorrected images was computed for standard 17-segment polar maps for each patient.
resultsMotion-corrected dual-phase CMRA images allow for visualization of the coronary arteries in both systole and diastole for all healthy subjects and cardiac patients. LV functional indices from healthy subjects result in good agreement with the reference method, underestimating stroke volume by 3.07 ± 3.26 mL and ejection fraction by 0.30 ± 1.01%. Motion correction improved delineation of the myocardium in PET images, resulting in an increased
conclusionThe proposed motion-corrected dual-phase CMRA and cardiac PET produces co-registered good quality images in both modalities in a single efficient examination of ~13 min.
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