Evidence map›Paper›PMID 30320668›Full record

ArticleJournal of pediatric gastroenterology and nutrition2019

Feeding Interventions Are Associated With Improved Outcomes in Children With Laryngeal Penetration.

Daniel R Duncan, Kara Larson, Kathryn Davidson, Kara May, Reza Rahbar, Rachel L Rosen

Abstract readEvaluation Study
In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. The nutrition profile and utility of banana puree as a liquid thickener for medically complex infants with dysphagia.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel R DuncanDivision of Gastroenterology, Hepatology and Nutrition, Aerodigestive Center.
Kara LarsonDivision of Gastroenterology, Hepatology and Nutrition, Aerodigestive Center.
Kathryn DavidsonCenter for Airway Disorders, Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, MA.
Kara MayDivision of Gastroenterology, Hepatology and Nutrition, Aerodigestive Center.
Reza RahbarCenter for Airway Disorders, Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, MA.
Rachel L RosenDivision of Gastroenterology, Hepatology and Nutrition, Aerodigestive Center.

Funding

STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI JONATHAN C KAGAN · 1986 to 2026
$32.4M
TRAINING IN PEDIATRIC GASTROENTEROLOGY &NUTRITIONT32DK007477 · NIDDK · CHILDREN'S HOSPITAL BOSTON · PI Scott B Snapper · 1986 to 2026
$13.3M
The impact of upper gastrointestinal dysmotility on aspiration-associated aerodigestive disorders in childrenR01DK097112 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI Rachel L Rosen · 2015 to 2026
$4.9M
NIDDK NIH HHS P30 DK034854NIDDK NIH HHS R01 DK097112NIDDK NIH HHS T32 DK007477
6 · The paper itself

Abstract

objectivesTo determine if children with laryngeal penetration on videofluoroscopic swallow study (VFSS) who received feeding interventions (thickened liquids, change in liquid flow rate, and/or method of liquid delivery) had improved symptoms and decreased hospitalizations compared with those without intervention.

methodsWe performed a retrospective cohort study of children under 2 years with laryngeal penetration on VFSS at our institution in 2015 to determine initial and follow-up VFSS findings, symptom improvement at follow-up, and hospitalization risk before and after VFSS. Proportions were compared with Fisher exact test and hospitalizations with paired t tests.

resultsWe evaluated 137 subjects with age 8.93 ± 0.59 months who had laryngeal penetration without aspiration on VFSS. Fifty-five percent had change in management, with 40% receiving thickening and 15% a change in flow rate. There was significant improvement in symptoms for children that had feeding intervention and this improvement was the greatest with thickening (OR 41.8, 95% CI 12.34-141.69, P < 0.001). On repeat VFSS, 26% had evidence of aspiration that was not captured on initial VFSS. Subjects had decreased total and pulmonary hospitalizations with feeding intervention and decreased pulmonary nights with thickening (P < 0.05).

conclusionsLaryngeal penetration appears to be clinically significant in children with oropharyngeal dysphagia and interventions to decrease its occurrence are associated with improved outcomes including decreased symptoms of concern and hospitalization nights. Thickening or other feeding intervention should be considered for all symptomatic children with laryngeal penetration on swallow study.

Indexed as

DeglutitionDeglutition DisordersFemaleFluoroscopyFollow-Up StudiesHumansInfantLaryngeal DiseasesMaleNutritional SupportRetrospective StudiesTreatment Outcome

Identifiers

PMID30320668
PMCPMC6501833

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.