ArticleThe neuroradiology journal2019
IgG4-related intracranial disease.
Article in The neuroradiology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- IgG4-Related Disease of the Skull and Skull Base-A Systematic Review and Report of Two Cases.World neurosurgery · 2021Pooled it
- IgG4-related hypertrophic pachymeningitis presenting with marked dural thickening, widespread white matter changes, and rectus gyrus transdiaphragmatic herniation into the sella turcica: a case report.Frontiers in immunology · 2026Article
- Management of isolated neurosarcoidosis mimicking cerebral meningiomatosis with multiple cranial neuropathies: An uncommon clinical scenario.Surgical neurology international · 2025Article
- Immunoglobulin G4-related spinal pachymeningitis: A case report.World journal of clinical cases · 2024Article
- Intracranial inflammatory pseudotumour related to IgG4: A very rare case.Caspian journal of internal medicine · 2024Article
- IgG4-related Inflammatory Pseudotumor with Imaging Findings Similar to Meningioma.Internal medicine (Tokyo, Japan) · 2023Article
- Epiduritis related to IgG4 disease: A very rare cause for spinal cord compression.Surgical neurology international · 2023Article
- Angiomatous meningioma associated with rapidly aggravated peritumoral leptomeningitis: A case report.Surgical neurology international · 2023Article
- Detecting immunoglobulin G4-related intracranial arteriopathy with magnetic resonance vessel wall imaging: a preliminary experience in two cases.BMC neurology · 2022Article
- Autoimmune disease of head and neck, imaging, and clinical review.The neuroradiology journal · 2022Review
- IgG4-related hypertrophic pachymeningitis with tumor-like intracranial and intracerebral lesions.Acta neurochirurgica · 2022Article
- Tolosa-Hunt Syndrome and IgG4 Diseases in Neuro-Ophthalmology.Annals of Indian Academy of Neurology · 2022Article
- Mind the gap: IgG4-related disease mimicking infectious cerebral mass lesions.European journal of medical research · 2022Article
- Immunoglobulin G4-related disease presenting as an intracranial mass extended from the infratemporal fossa.Surgical neurology international · 2022Article
- IgG4-related hypophysitis.Endocrine · 2021Review
- Hypertrophic Pachymeningitis and Choroid Plexitis in IgG-4-Related Disease.Neurology. Clinical practice · 2021Article
- Successful treatment of IgG4-related hypertrophic pachymeningitis with induction rituximab and dexamethasone followed by maintenance rituximab.Clinical case reports · 2021Article
- Immunoglobulin G4-related disease of the cavernous sinus with orbit invasion - A case report.Surgical neurology international · 2021Article
- IgG4-Related Inflammatory Pseudotumor Involving the Clivus: A Case Report and Literature Review.Frontiers in endocrinology · 2021Review
- Two cases of immunoglobulin G4 (IgG4)-related hypophysitis diagnosed without pituitary biopsy.Therapeutic advances in endocrinology and metabolism · 2020Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
IgG4-related disease (IgG4-RD) is a multi-organ chronic inflammatory process caused by infiltration of IgG4-positive plasma cells in one or more organs. Intracranial involvement has only recently become better recognized. Our case series adds to the growing literature on the varying presentations of intracranial IgG4 by describing the clinical and imaging findings of three patients who presented to our institution with intracranial involvement. Our first patient presented with a mass-forming IgG4 pachymeningitis mimicking a sphenoid wing meningioma, which is to our knowledge the largest mass-forming pachymeningitis published in the literature. Our second case depicts another presentation of extensive IgG4 pachymeningitis involving both cavernous sinuses and surrounding Meckel's caves. The third case describes a patient with presumed lymphocytic hypophysitis, which was later determined to be IgG4-related hypophysitis with concomitant pachymeningitis and perineural spread along the optic nerves. The delayed diagnoses in our cases illustrates the diagnostic challenge that clinicians face in differentiating intracranial IgG4-RD from other infiltrative diseases such as sarcoidosis, granulomatous disease, tuberculosis and lymphoma. Earlier consideration of IgG4-related hypophysitis and hypertrophic pachymeningitis in the differential diagnosis can prevent significant morbidity including unnecessary surgical intervention and organ failure secondary to extensive fibrosis.
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