Evidence map›Paper›PMID 30320429›Full record

ArticleCancer2018

A feasibility study of breast cancer genetic risk assessment in a federally qualified health center.

Kent F Hoskins, Silvia Tejeda, Ganga Vijayasiri, Ifeanyi Beverly Chukwudozie, Mylene H Remo, Hiral A Shah, Ivy E Abraham, Lara E Balay, Tara K Maga, Ericka R Searles and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Risk-Stratified Breast Cancer Screening in Malaysia: Challenges and Opportunities.Asian Pacific journal of cancer prevention : APJCP · 2024
    Review
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  10. Review
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  12. Article
  13. Increasing access to individualized medicine: a matched-cohort study examining Latino participant experiences of genomic screening.Genetics in medicine : official journal of the American College of Medical Genetics · 2021
    Article
  14. Young Women's Perspectives on Being Screened for Hereditary Breast and Ovarian Cancer Risk During Routine Primary Care.Women's health issues : official publication of the Jacobs Institute of Women's Health
    Article
  15. Healthcare Predictors of Information Dissemination About Genetic Risks.Cancer control : journal of the Moffitt Cancer Center
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Kent F HoskinsSection of Hematology and Oncology, Department of Medicine, University of Illinois at Chicago College of Medicine, Chicago, Illinois.
Silvia TejedaInstitute for Health Research and Policy, School of Public Health, University of Illinois at Chicago, Chicago, Illinois.ORCID 0000-0001-8728-3506
Ganga VijayasiriInstitute for Health Research and Policy, School of Public Health, University of Illinois at Chicago, Chicago, Illinois.
Ifeanyi Beverly ChukwudozieInstitute for Health Research and Policy, School of Public Health, University of Illinois at Chicago, Chicago, Illinois.
Mylene H RemoSection of Hematology and Oncology, Department of Medicine, University of Illinois at Chicago College of Medicine, Chicago, Illinois.
Hiral A ShahSection of Hematology and Oncology, Department of Medicine, University of Illinois at Chicago College of Medicine, Chicago, Illinois.
Ivy E AbrahamSection of Hematology and Oncology, Department of Medicine, University of Illinois at Chicago College of Medicine, Chicago, Illinois.
Lara E BalaySection of Hematology and Oncology, Department of Medicine, University of Illinois at Chicago College of Medicine, Chicago, Illinois.
Tara K MagaSection of Hematology and Oncology, Department of Medicine, University of Illinois at Chicago College of Medicine, Chicago, Illinois.
Ericka R SearlesChicago Family Health Center, Chicago, Illinois.
Veena J KorahChicago Family Health Center, Chicago, Illinois.
Alana BiggersSection of General Internal Medicine, University of Illinois at Chicago College of Medicine, Chicago, Illinois.
Melinda R StolleyInstitute for Health Research and Policy, School of Public Health, University of Illinois at Chicago, Chicago, Illinois.
Richard B WarneckeInstitute for Health Research and Policy, School of Public Health, University of Illinois at Chicago, Chicago, Illinois.
Chicago Department of Public Health · USUniversity of Illinois Chicago · USErie Family Health Center · US

Funding

Strengthening Stakeholder Engagement in Human Research Protections.UL1TR002003 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KARNIK, NIRANJAN SUBHASH, MERMELSTEIN, ROBIN J. · 2016 to 2024
$33.7M
UIC CENTERS FOR POPULATION HEALTH AND HEALTH DISPARITIESP50CA106743 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WARNECKE, RICHARD · 2003 to 2016
$19.3M
Research Education CoreU54CA202997 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI NAYLOR, KEITH BRIAN, TUSSING-HUMPHREYS, LISA · 2015 to 2024
$13.8M
Research Education CoreU54CA203000 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GIACHELLO, AIDA L · 2015 to 2024
$12.4M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR029879 · NCRR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MAZZONE, THEODORE · 2009 to 2011
$11.0M
The Chicago Cancer Health Equity Collaborative (ChicagoCHEC)U54CA202995 · NCI · NORTHEASTERN ILLINOIS UNIVERSITY · PI CIECIERSKI, CHRISTINA · 2015 to 2024
$9.5M
Training & Education CoreP20CA202908 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MATTHEWS, ALICIA K · 2015 to 2018
$858k
National Center for Advancing Translational Sciences of the National Institutes of Health UL1RR029879NCATS NIH HHS UL1 TR002003NCI NIH HHS 2P50CA106743NCI NIH HHS P20 CA202908NCI NIH HHS P50 CA106743NCI NIH HHS U54 CA202995NCI NIH HHS U54 CA202997NCI NIH HHS U54 CA203000NCRR NIH HHS UL1 RR029879
6 · The paper itself

Abstract

backgroundThe US Preventive Services Task Force (USPSTF) endorses routine screening for genetic risk of breast and/or ovarian cancer as a component of primary health care. Implementation of this recommendation may prove challenging, especially in clinics serving disadvantaged communities.

methodsThe authors tested the feasibility of implementing the USPSTF mandate at a federally qualified health center (FQHC) to identify women who were eligible for genetic counseling (GC). A 12-month usual-care phase was followed by a 12-month intervention phase, during which time cancer genetic risk assessment (CGRA) was systematically performed for all women aged 25 to 69 years who presented for an annual examination. Women who were eligible for GC were recruited to participate in the study.

resultsAfter initiating CGRA, 112 women who were eligible for GC consented to study participation, and 56% of them received a referral for GC from their primary care physician. A subgroup of 50 participants were seen by the same primary care physician during both the usual-care and intervention phases. None of these patients was referred for GC during usual care, compared with 64% after the initiation of CGRA (P < .001). Only 16% of referred participants attended a GC session.

conclusionsImplementing USPSTF recommendations for CGRA as a standard component of primary health care in FQHCs is feasible and improves referral of minority women for GC, but more work is needed to understand the beliefs and barriers that prevent many underserved women from accessing cancer genetic services.

Indexed as

Genetic TestingHealth Plan ImplementationAdultAgedBreast NeoplasmsChicagoFeasibility StudiesFemaleFinancing, GovernmentGenetic CounselingHealth Status DisparitiesHumansMass ScreeningMiddle AgedOvarian NeoplasmsPhysicians, Primary Carebreast cancergenetic counselinggenetic susceptibilityhealth disparitiesrisk assessment

Identifiers

PMID30320429
PMCPMC6214782
OpenAlexW2897050873

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.