ArticleACS omega2018
Multifunctional System Polyaniline-Decorated ZIF-8 Nanoparticles as a New Chemo-Photothermal Platform for Cancer Therapy.
Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 60 citations in OpenAlex.
- Seeded-Growth of ZIF-8 onto Magnetic Nanoparticles: Smart Nanocarriers with Ultrahigh Drug Loading for AMF-Triggered Release.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Article
- Improving the drug delivery performance of ZIF-8 with amine functionalization as a 5-fluorouracil nanocarrier.Scientific reports · 2025Article
- Meniran (RSC advances · 2025Article
- Highly dispersive PEI-modified CDs@ZIF-L dual-emitting fluorescent sensor for detecting metal ions.RSC advances · 2023Article
- Fabricating a PDA-Liposome Dual-Film Coated Hollow Mesoporous Silica Nanoplatform for Chemo-Photothermal Synergistic Antitumor Therapy.Pharmaceutics · 2023Article
- Stability of ZIF-8 Nanoparticles in Most Common Cell Culture Media.Molecules (Basel, Switzerland) · 2022Article
- Highly dispersive AuNCs/ChOx@ZIF-8/PEI nanocomplexes for fluorescent detection of cholesterol in human serum.Mikrochimica acta · 2022Article
- Zinc-Based Metal-Organic Frameworks in Drug Delivery, Cell Imaging, and Sensing.Molecules (Basel, Switzerland) · 2021Review
- MOFs Derived Hetero-ZnO/FeNanomaterials (Basel, Switzerland) · 2021Article
- pH-triggered degradation and release of doxorubicin from zeolitic imidazolate framework-8 (ZIF8) decorated with polyacrylic acid.RSC advances · 2021Article
- Liposomal Dendritic Cell Vaccine in Breast Cancer Immunotherapy.ACS omega · 2021Article
- Mid-Infrared Imaging Is Able to Characterize and Separate Cancer Cell Lines.Pathology oncology research : POR · 2020Article
- Recent Advances of Polyaniline-Based Biomaterials for Phototherapeutic Treatments of Tumors and Bacterial Infections.Bioengineering (Basel, Switzerland) · 2020Review
- Recent developments on zinc(ii) metal-organic framework nanocarriers for physiological pH-responsive drug delivery.MedChemComm · 2019Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyaniline-decorated ZIF-8 nanoparticles (nPANI@nZIF-8) were easily synthesized and employed as a multifunctional system for the delivery of the antitumor drug 5-fluorouracil (5-FU). Because of the storage ability of the network ZIF-8, 68% of the total amount of the 5-FU drug was released at pH 5.2. The system exhibits absorption in the near-infrared (NIR) region and can be used in the photothermal therapy owing to the presence of nPANI, which has a strong NIR uptake. This absorption causes local hyperthermia by aiding in the diffusion of the drug molecules contained by the polymer into nPANI@nZIF-8/5-FU achieving a greater release of the 5-FU drug, about 80% activated by an NIR laser (λ = 980 nm). This hyperthermia reached about 70 °C (200 μL, 1 mg mL
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.