Evidence map›Paper›PMID 30320288›Full record

ArticleACS omega2018

Validated HPLC-MS/MS Method To Quantify Low Levels of Domoic Acid in Plasma and Urine after Subacute Exposure.

Sara Shum, Jay S Kirkwood, Jing Jing, Rebekah Petroff, Brenda Crouthamel, Kimberly S Grant, Thomas M Burbacher, Wendel L Nelson, Nina Isoherranen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sara ShumDepartment of Pharmaceutics, Department of Environmental and Occupational Health Sciences, Washington National Primate Research Center, Center on Human Development and Disability, and Department of Medicinal Chemistry, University of Washington, Health Sciences Building, 1959 NE Pacific Street, Seattle, Washington 98195, United States.
Jay S KirkwoodDepartment of Pharmaceutics, Department of Environmental and Occupational Health Sciences, Washington National Primate Research Center, Center on Human Development and Disability, and Department of Medicinal Chemistry, University of Washington, Health Sciences Building, 1959 NE Pacific Street, Seattle, Washington 98195, United States.
Jing JingDepartment of Pharmaceutics, Department of Environmental and Occupational Health Sciences, Washington National Primate Research Center, Center on Human Development and Disability, and Department of Medicinal Chemistry, University of Washington, Health Sciences Building, 1959 NE Pacific Street, Seattle, Washington 98195, United States.
Rebekah PetroffDepartment of Pharmaceutics, Department of Environmental and Occupational Health Sciences, Washington National Primate Research Center, Center on Human Development and Disability, and Department of Medicinal Chemistry, University of Washington, Health Sciences Building, 1959 NE Pacific Street, Seattle, Washington 98195, United States.
Brenda CrouthamelDepartment of Pharmaceutics, Department of Environmental and Occupational Health Sciences, Washington National Primate Research Center, Center on Human Development and Disability, and Department of Medicinal Chemistry, University of Washington, Health Sciences Building, 1959 NE Pacific Street, Seattle, Washington 98195, United States.
Kimberly S GrantDepartment of Pharmaceutics, Department of Environmental and Occupational Health Sciences, Washington National Primate Research Center, Center on Human Development and Disability, and Department of Medicinal Chemistry, University of Washington, Health Sciences Building, 1959 NE Pacific Street, Seattle, Washington 98195, United States.
Thomas M BurbacherDepartment of Pharmaceutics, Department of Environmental and Occupational Health Sciences, Washington National Primate Research Center, Center on Human Development and Disability, and Department of Medicinal Chemistry, University of Washington, Health Sciences Building, 1959 NE Pacific Street, Seattle, Washington 98195, United States.
Wendel L NelsonDepartment of Pharmaceutics, Department of Environmental and Occupational Health Sciences, Washington National Primate Research Center, Center on Human Development and Disability, and Department of Medicinal Chemistry, University of Washington, Health Sciences Building, 1959 NE Pacific Street, Seattle, Washington 98195, United States.
Nina IsoherranenDepartment of Pharmaceutics, Department of Environmental and Occupational Health Sciences, Washington National Primate Research Center, Center on Human Development and Disability, and Department of Medicinal Chemistry, University of Washington, Health Sciences Building, 1959 NE Pacific Street, Seattle, Washington 98195, United States.
University of Washington · US

Funding

Washington National Primate Research CenterP51OD010425 · OD · UNIVERSITY OF WASHINGTON · PI Mari Ostendorf · 2012 to 2026
$201.8M
Intellectual and Developmental Disabilities Research CenterU54HD083091 · NICHD · UNIVERSITY OF WASHINGTON · PI DOHERTY, DANIEL · 2014 to 2019
$7.9M
Developmental Neurotoxicity of Domoic Acid in a Nonhuman Primate ModelR01ES023043 · NIEHS · UNIVERSITY OF WASHINGTON · PI BURBACHER, THOMAS M · 2014 to 2019
$4.3M
NICHD NIH HHS U54 HD083091NIEHS NIH HHS R01 ES023043NIH HHS P51 OD010425
6 · The paper itself

Abstract

Domoic acid (DA) is a marine neurotoxin produced by several species of

Identifiers

PMID30320288
PMCPMC6175497
OpenAlexW2894363863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.