Evidence map›Paper›PMID 30320217›Full record

ArticlemSystems

Persistent Interactions with Bacterial Symbionts Direct Mature-Host Cell Morphology and Gene Expression in the Squid-Vibrio Symbiosis.

Natacha Kremer, Eric J Koch, Adil El Filali, Lawrence Zhou, Elizabeth A C Heath-Heckman, Edward G Ruby, Margaret J McFall-Ngai

Open access · goldAbstract read
In one paragraph

Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Maintaining microbiota across diverse symbiotic organs inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. The cytokine MIF controls daily rhythms of symbiont nutrition in an animal-bacterial association.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  9. Article
  10. Trends in Symbiont-Induced Host Cellular Differentiation.Results and problems in cell differentiation · 2020
    Article
  11. Critical symbiont signals drive both local and systemic changes in diel and developmental host gene expression.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Natacha KremerDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0001-5678-9416
Eric J KochDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Adil El FilaliLaboratoire de Biométrie et Biologie Evolutive, Université de Lyon, Université Lyon 1, CNRS, UMR 5558, Villeurbanne, France.
Lawrence ZhouDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Elizabeth A C Heath-HeckmanDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Edward G RubyDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Margaret J McFall-NgaiDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
University of Hawaiʻi at Mānoa · USUniversité Claude Bernard Lyon 1 · FRUniversity of Wisconsin–Madison · US

Funding

Vibrio fischeri as a Model for Bacterial ColonizationR37AI050661 · NIAID · UNIVERSITY OF HAWAII AT MANOA · PI MARGARET J MC FALL-NGAI, Edward G Ruby · 2018 to 2026
$5.4M
Vibrio fischeri as a model of Bacterial ColonizationR01AI050661 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI MC FALL-NGAI, MARGARET J, RUBY, EDWARD G · 2002 to 2016
$5.0M
Vibrio Virulence Determinants in a Benign ColonizationR01OD011024 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI MC FALL-NGAI, MARGARET J, RUBY, EDWARD G · 2012 to 2020
$3.9M
NIAID NIH HHS R01 AI050661NIAID NIH HHS R37 AI050661NIH HHS R01 OD011024
6 · The paper itself

Abstract

In horizontally transmitted symbioses, structural, biochemical, and molecular features both facilitate host colonization by specific symbionts and mediate their persistent carriage. In the association between the squid

Indexed as

accommodationdevelopmentEuprymna scolopespersistent symbiosistranscriptomicsVibrio fischeri

Identifiers

PMID30320217
PMCPMC6172772
OpenAlexW2895744941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.