Evidence map›Paper›PMID 30320202›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2018

The conceptual relevance of assessment measures in patients with mild/mild-moderate Alzheimer's disease.

Ann Hartry, Natalie V J Aldhouse, Tamara Al-Zubeidi, Myrlene Sanon, Richard G Stefanacci, Sarah L Knight

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Outcome measures for Alzheimer's disease: A global inter-societal Delphi consensus.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ann HartryLundbeck, Deerfield, IL, USA.
Natalie V J AldhouseDRG Abacus, Manchester, UK.
Tamara Al-ZubeidiDRG Abacus, Bicester, Oxfordshire, UK.
Myrlene SanonOtsuka Pharmaceutical Development & Commercialization, Inc. Princeton, NJ, USA.
Richard G StefanacciJefferson College of Population Health, Thomas Jefferson University, Philadelphia, PA, USA.
Sarah L KnightDRG Abacus, Bicester, Oxfordshire, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aims to evaluate the conceptual relevance of four measures of disease activity in patients with mild/mild-moderate Alzheimer's disease (AD): (1) the Alzheimer's Disease Assessment Scale-Cognitive Subscale; (2) the Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory; (3) the Neuropsychiatry Inventory; and (4) the Dependence Scale.

methodsA conceptual model depicting patient experience of mild AD was developed via literature review; concepts were compared with the items of the four measures. Relevance of the concepts included in the four measures was evaluated by patients with mild AD in a survey and follow-up interviews.

resultsThe four measures assessed few of the symptoms/impacts of mild AD identified within the literature. Measured items addressing emotional impacts were deemed most relevant by participants but were included in the measures only superficially. DISCUSSION: The four assessment measures do not appear to capture the concepts most relevant to/important to patients with mild/mild-moderate AD.

Indexed as

Conceptual relevanceMild/mild-moderate Alzheimer's diseaseOutcome measuresPatient-reported outcome (PRO)Qualitative interviewsQuantitative survey

Identifiers

PMID30320202
PMCPMC6180432

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.