Evidence map›Paper›PMID 30320116›Full record

ReviewFrontiers in medicine2018

The Role of CXCR3 and Its Chemokine Ligands in Skin Disease and Cancer.

Paula T Kuo, Zhen Zeng, Nazhifah Salim, Stephen Mattarollo, James W Wells, Graham R Leggatt

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 1 synthesis or guideline pooled it, 166 citations in OpenAlex.

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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Paula T KuoDiamantina Institute, Translational Research Institute, University of Queensland, Brisbane, QLD, Australia.
Zhen ZengDiamantina Institute, Translational Research Institute, University of Queensland, Brisbane, QLD, Australia.
Nazhifah SalimDiamantina Institute, Translational Research Institute, University of Queensland, Brisbane, QLD, Australia.
Stephen MattarolloDiamantina Institute, Translational Research Institute, University of Queensland, Brisbane, QLD, Australia.
James W WellsDiamantina Institute, Translational Research Institute, University of Queensland, Brisbane, QLD, Australia.
Graham R LeggattDiamantina Institute, Translational Research Institute, University of Queensland, Brisbane, QLD, Australia.
University of Queensland · AUTranslational Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemokines and their receptors play an important role in the recruitment, activation and differentiation of immune cells. The chemokine receptor, CXCR3, and its ligands, CXCL9, CXCL10, and CXCL11 are key immune chemoattractants during interferon-induced inflammatory responses. Inflammation of the skin resulting from infections or autoimmune disease drives expression of CXCL9/10/11 and the subsequent recruitment of effector, CXCR3

Indexed as

CXCL9/10/11CXCR3melanomaskin cancersquamous cell carcinoma

Identifiers

PMID30320116
PMCPMC6167486
OpenAlexW2891241542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.