Evidence map›Paper›PMID 30320041›Full record

ArticleEuropean journal of sports & exercise science2018

Age, Sex and Weight Effects on Lactate and Leukocyte Response to Exercise in Children and Adolescents.

Jen Jen Chen, Elizabeth Gendy, Sharon Leu, Frank Zaldivar, Pietro Gallassetti, Elieze Nussbaum, Dan Cooper, Shlomit Random-Aizik

Open access · greenAbstract read
In one paragraph

Article in European journal of sports & exercise science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jen Jen ChenPediatric Exercise and Genomics Research Center, University of California, USA.
Elizabeth GendyMiller Children's Hospital, Long Beach, USA.
Sharon LeuPediatric Exercise and Genomics Research Center, University of California, USA.
Frank ZaldivarPediatric Exercise and Genomics Research Center, University of California, USA.
Pietro GallassettiPediatric Exercise and Genomics Research Center, University of California, USA.
Elieze NussbaumMiller Children's Hospital, Long Beach, USA.
Dan CooperPediatric Exercise and Genomics Research Center, University of California, USA.
Shlomit Random-AizikPediatric Exercise and Genomics Research Center, University of California, USA.
Boston Children's Hospital · US

Funding

Peripheral Blood Mononuclear Cells, Exercise, and Children: Initial MechanismsP01HD048721 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M · 2006 to 2016
$13.6M
INSTITUTE FOR CLINICAL AND TRANSLATIONAL SCIENCEUL1RR031985 · NCRR · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M · 2010 to 2011
$7.2M
U.C. Irvine Multidisciplinary Exercise Science Training ProgramT32AR047752 · NIAMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI CAIOZZO, VINCENT JAMES, COOPER, DAN M · 2003 to 2018
$2.5M
NCRR NIH HHS UL1 RR031985NIAMS NIH HHS T32 AR047752NICHD NIH HHS P01 HD048721
6 · The paper itself

Abstract

Post-exercise leucocytosis has been found in children and adults in response to exercise. When normalized to the work performed, children demonstrate a lower lactate response to exercise than in adults. This study examines the association between leukocyte and lactate response in children following exercise. 148 healthy children participated in this study. Each subject performed a ramp exercise on a cycle ergometer followed by ten 2-minute bouts of constant work rate separated by 1-minute rest intervals. Lactate, leukocyte and leukocyte subtype levels were taken pre- and post-exercise. Older children showed a significantly higher pre-to post-exercise leukocyte compared to younger children (3599 ± 165 cells/mL, 2544 ± 163, p<0.0001). Compared to older children, younger children demonstrated a smaller median fold change in lactate (2.7 (1.4-8.1), 4.1 (1.7-29.6)) and leukocyte levels (1.4 (1.0-2.1), 1.6 (1.2-2.8)) after exercise, with a larger leukocyte to lactate fold change ratio.

conclusionYounger children have a greater leukocyte to lactate fold change ratio compared to older children. This finding may be due to the lower anaerobic dependence that is found in younger children.

Indexed as

ExerciseInflammationLactateLeukocytePaediatrics

Identifiers

PMID30320041
PMCPMC6177222
OpenAlexW2887792394

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.