Evidence map›Paper›PMID 30319961›Full record

ArticleFrontiers in oncology2018

Initial Report of a Phase I Study of LY2510924, Idarubicin, and Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia.

Prajwal Boddu, Gautam Borthakur, Mythili Koneru, Xuelin Huang, Kiran Naqvi, William Wierda, Prithviraj Bose, Elias Jabbour, Zeev Estrov, Jan Burger and 9 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. The role of CXC chemokines and receptors in breast cancer.Clinical and experimental medicine · 2025
    Review
  6. Selective PET imaging of CXCR4 using the AlEuropean journal of nuclear medicine and molecular imaging · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. CXC chemokine receptor 4 (CXCR4) blockade in cancer treatment.Journal of cancer research and clinical oncology · 2023
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Regulation of Malignant Myeloid Leukemia by Mesenchymal Stem Cells.Frontiers in cell and developmental biology · 2022
    Review
  19. Review
  20. Therapeutic Targeting of the Leukaemia Microenvironment.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Prajwal BodduDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Gautam BorthakurDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Mythili KoneruEli Lilly and Company, Indianapolis, IN, United States.
Xuelin HuangDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Kiran NaqviDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
William WierdaDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Prithviraj BoseDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Elias JabbourDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Zeev EstrovDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Jan BurgerDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Yesid AlvaradoDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
April DeshmukhDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Ami PatelDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Antonio CavazosDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Lina HanDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Jorge E CortesDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Hagop KantarjianDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Michael AndreeffDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
Marina KonoplevaDepartment of Leukemia, University of Texas at MD Anderson Cancer Center, Houston, TX, United States.
The University of Texas MD Anderson Cancer Center · USEli Lilly (United States) · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute myeloid leukemiaCXC4cytarabineidarubicinLY2510924relapsed refractory

Identifiers

PMID30319961
PMCPMC6167965
OpenAlexW2892491493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.