Evidence map›Paper›PMID 30319935›Full record

ArticleCurrent treatment options in psychiatry2018

Psychosocial Treatment of Irritability in Youth.

Katharina Kircanski, Michal E Clayton, Ellen Leibenluft, Melissa A Brotman

Open access · greenAbstract read
In one paragraph

Article in Current treatment options in psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 62 citations in OpenAlex.

  1. Trial
  2. Trial
  3. An Exposure-Based Cognitive-Behavioral Therapy for Youth with Severe Irritability: Feasibility and Preliminary Efficacy.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Trial
  4. Article
  5. Substance-involved child-to-parent violence.Drug and alcohol review · 2025
    Article
  6. Observational
  7. A network approach to the investigation of childhood irritability: probing frustration using social stimuli.Journal of child psychology and psychiatry, and allied disciplines · 2024
    Article
  8. Article
  9. Irritability in Youths: A Critical Integrative Review.The American journal of psychiatry · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review: Defining Positive Emotion Dysregulation: Integrating Temperamental and Clinical Perspectives.Journal of the American Academy of Child and Adolescent Psychiatry · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Katharina KircanskiEmotion and Development Branch, National Institute of Mental Health.
Michal E ClaytonEmotion and Development Branch, National Institute of Mental Health.
Ellen LeibenluftEmotion and Development Branch, National Institute of Mental Health.
Melissa A BrotmanEmotion and Development Branch, National Institute of Mental Health.
National Institute of Mental Health · JPNational Institute of Mental Health · US

Funding

The Pathophysiology and Treatment Of Children With Severe Mood DysregulationZIAMH002786 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI LEIBENLUFT, ELLEN · 2009 to 2023
$34.0M
Unit on Neuroscience and Novel TherapeuticsZIAMH002969 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BROTMAN, MELISSA · 2019 to 2025
$13.8M
The Phenomenology And Neurophysiology Of Juvenile Bipolar DisorderZIAMH002778 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI LEIBENLUFT, ELLEN · 2009 to 2017
$10.8M
Intramural NIH HHS ZIA MH002778Intramural NIH HHS ZIA MH002786
6 · The paper itself

Abstract

purpose of reviewChronic, severe irritability is a common presenting problem in children and adolescents. Disruptive mood dysregulation disorder (DMDD) was added to the DSM-5 in recognition of this public health need. Currently there are no well-established, evidence-based pharmacological or psychosocial treatments specifically for DMDD. Here, we focus on psychosocial interventions. In addition to reviewing published research, we present preliminary, open trial data on a novel exposure-based cognitive-behavioral therapy (CBT) targeting severe irritability, as is present in DMDD. RECENT

findingsIn the published literature, parent management training (PMT) comprises parent-based interventions designed to treat youth disruptive behavior. Child-based interventions for disruptive behavior include CBT focused on social cognition and problem-solving. Based on identified treatment gaps for severe irritability in children and adolescents, novel psychosocial interventions are being developed. We have developed a CBT for severe irritability that integrates exposure techniques, drawn from anxiety treatment, with selected PMT techniques. Data from an open pilot trial ( SUMMARY: Promising psychosocial treatments are being developed for DMDD. Future directions include testing these new therapies against extant interventions. Increased research on the biological and psychological mechanisms mediating irritability will further bridge the treatment gap for youth and families.

Indexed as

cognitive-behavioral therapydisruptive mood dysregulation disorderexposureirritabilityparent management training

Identifiers

PMID30319935
PMCPMC6181450
OpenAlexW2790595714

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.