Evidence map›Paper›PMID 30319933›Full record

ArticleCurrent epidemiology reports2018

Ambient and Traffic-Related Air Pollution Exposures as Novel Risk Factors for Metabolic Dysfunction and Type 2 Diabetes.

Tanya L Alderete, Zhanghua Chen, Claudia M Toledo-Corral, Zuelma A Contreras, Jeniffer S Kim, Rima Habre, Leda Chatzi, Theresa Bastain, Carrie V Breton, Frank D Gilliland

Open access · greenAbstract read
In one paragraph

Article in Current epidemiology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

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  10. Air pollution and health prevention: A document of reflection.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Tanya L AldereteUniversity of Southern California, Department of Preventive Medicine, Division of Environmental Health, Los Angeles, California, USA.
Zhanghua ChenUniversity of Southern California, Department of Preventive Medicine, Division of Environmental Health, Los Angeles, California, USA.
Claudia M Toledo-CorralUniversity of Southern California, Department of Preventive Medicine, Division of Environmental Health, Los Angeles, California, USA.
Zuelma A ContrerasUniversity of Southern California, Department of Preventive Medicine, Division of Environmental Health, Los Angeles, California, USA.
Jeniffer S KimUniversity of Southern California, Department of Preventive Medicine, Division of Environmental Health, Los Angeles, California, USA.
Rima HabreUniversity of Southern California, Department of Preventive Medicine, Division of Environmental Health, Los Angeles, California, USA.
Leda ChatziUniversity of Southern California, Department of Preventive Medicine, Division of Environmental Health, Los Angeles, California, USA.
Theresa BastainUniversity of Southern California, Department of Preventive Medicine, Division of Environmental Health, Los Angeles, California, USA.
Carrie V BretonUniversity of Southern California, Department of Preventive Medicine, Division of Environmental Health, Los Angeles, California, USA.
Frank D GillilandUniversity of Southern California, Department of Preventive Medicine, Division of Environmental Health, Los Angeles, California, USA.
University of Southern California · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
Training Grant in Genomic Analysis and InterpretationT32ES013678 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GAUDERMAN, WILLIAM JAMES, MCCONNELL, ROB S · 2006 to 2023
$5.6M
Southern California Children's Environmental Health Center (SC-CEHC)P01ES022845 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCCONNELL, ROB S · 2013 to 2018
$4.0M
NIEHS NIH HHS P01 ES022845NIEHS NIH HHS P30 ES007048NIEHS NIH HHS T32 ES013678
6 · The paper itself

Abstract

purpose of reviewDiabetes mellitus is a top contributor to the global burden of mortality and disability in adults. There has also been a slow, but steady rise in prediabetes and type 2 diabetes in youth. The current review summarizes recent findings regarding the impact of increased exposure to air pollutants on the type 2 diabetes epidemic. RECENT

findingsHuman and animal studies provide strong evidence that exposure to ambient and traffic-related air pollutants such as particulate matter (PM), nitrogen dioxide (NO SUMMARY: Current epidemiological evidence suggests that increased air pollution exposure contributes to alterations in insulin signaling, glucose metabolism, and beta (β)-cell function. Future work is needed to identify the specific detrimental pollutants that alter glucose metabolism. Additionally, advanced tools and new areas of investigation present unique opportunities to study the underlying mechanisms, including intermediate pathways, that link increased air pollution exposure with type 2 diabetes onset.

Indexed as

air pollutionbeta-cell functioninsulin resistancetype 2 diabetes

Identifiers

PMID30319933
PMCPMC6178230
OpenAlexW2796900890

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.