ArticleBiomedical optics express2018
Determination of confocal profile and curved focal plane for OCT mapping of the attenuation coefficient.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Optimizing optical coherence tomography to detect occult spermatozoa in rat testis after induced non-obstructive azoospermia.Journal of biomedical optics · 2025Article
- Basis function model to extract the combined confocal and fall-off function from multiple optical coherence tomography A-scans.Journal of biomedical optics · 2025Article
- Accurate attenuation characterization in optical coherence tomography using multi-reference phantoms and deep learning.Biomedical optics express · 2024Article
- Optical-coherence-tomography-based deep-learning scatterer-density estimator using physically accurate noise model.Biomedical optics express · 2024Article
- Confocal corrected attenuation coefficient imaging in phantoms andBiomedical optics express · 2023Article
- Unleashing the power of optical attenuation coefficients to facilitate segmentation strategies in OCT imaging of age-related macular degeneration: perspective.Biomedical optics express · 2023Article
- Investigation of methods to extract confocal function parameters for the depth resolved determination of attenuation coefficients using OCT in intralipid samples, titanium oxide phantoms, and in vivo human retinas.Biomedical optics express · 2021Article
- Attenuation coefficient estimation in Fourier-domain OCT of multi-layered phantoms.Biomedical optics express · 2021Article
- Analysis of attenuation coefficient estimation in Fourier-domain OCT of semi-infinite media.Biomedical optics express · 2020Article
- [Progress of quantitative intravascular optical coherence tomography].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020Review
- Robust, accurate depth-resolved attenuation characterization in optical coherence tomography.Biomedical optics express · 2020Article
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Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The attenuation coefficient has proven to be a useful tool in numerous biological applications, but accurate calculation is dependent on the characterization of the confocal effect. This study presents a method to precisely determine the confocal effect and its focal plane within a sample by examining the ratio of two optical coherence tomography (OCT) images. The method can be employed to produce a single-value estimate, or a 2D map of the focal plane accounting for the curvature or tilt within the sample. Furthermore, this method is applicable to data obtained with both high numerical aperture (NA) and low-NA lenses, thereby furthering the applicability of the attenuation coefficient to high-NA OCT data. We test and validate this method using standard samples of Intralipid 20% and 5%, improving the accuracy to 99% from 65% compared to the traditional method and preliminarily show applicability to real biological data of glioblastoma acquired
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Registered trials
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