Evidence map›Paper›PMID 30319888›Full record

ArticleBiomedical optics express2018

Direct approach to compute Jacobians for diffuse optical tomography using perturbation Monte Carlo-based photon "replay".

Ruoyang Yao, Xavier Intes, Qianqian Fang

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 82 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ruoyang YaoDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 8th Street, Troy, NY 12180, USA.
Xavier IntesDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 8th Street, Troy, NY 12180, USA.
Qianqian FangDepartment of Bioengineering, Northeastern University, 360 Huntington Ave, Boston, MA 02115, USA.
Rensselaer Polytechnic Institute · USNortheastern University · US

Funding

Role of tumor heterogeneity on receptor engagementR01CA207725 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, CORR, DAVID THOMAS · 2017 to 2021
$3.0M
Next-generation Monte Carlo eXtreme Light Transport Simulation PlatformR01GM114365 · NIGMS · NORTHEASTERN UNIVERSITY · PI FANG, QIANQIAN · 2015 to 2023
$2.9M
Ultra-high-density, compressive and media- adaptive optical breast tomography platformR01CA204443 · NCI · NORTHEASTERN UNIVERSITY · PI FANG, QIANQIAN · 2016 to 2025
$2.5M
Time-Resolved Wide-Field Molecular Optical TomographyR01EB019443 · NIBIB · RENSSELAER POLYTECHNIC INSTITUTE · PI INTES, XAVIER · 2015 to 2018
$1.7M
NCI NIH HHS R01 CA204443NCI NIH HHS R01 CA207725NIBIB NIH HHS R01 EB019443NIGMS NIH HHS R01 GM114365
6 · The paper itself

Abstract

Perturbation Monte Carlo (pMC) has been previously proposed to rapidly recompute optical measurements when small perturbations of optical properties are considered, but it was largely restricted to changes associated with prior tissue segments or regions-of-interest. In this work, we expand pMC to compute spatially and temporally resolved sensitivity profiles, i.e. the Jacobians, for diffuse optical tomography (DOT) applications. By recording the pseudo random number generator (PRNG) seeds of each detected photon, we are able to "replay" all detected photons to directly create the 3D sensitivity profiles for both absorption and scattering coefficients. We validate the replay-based Jacobians against the traditional adjoint Monte Carlo (aMC) method, and demonstrate the feasibility of using this approach for efficient 3D image reconstructions using

Indexed as

(110.4234) Multispectral and hyperspectral imaging(170.3660) Light propagation through tissue(170.5280) Photon migration(170.7050) Tomography(230.6120) Spatial light modulators

Identifiers

PMID30319888
PMCPMC6179418
OpenAlexW2889994066

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.