Evidence map›Paper›PMID 30319862›Full record

ArticleFood science and biotechnology2018

A comparative study of the antithrombotic effect through activated endothelium of garlic powder and tomato extracts using a rodent model of collagen and epinephrine induced thrombosis.

Leeseon Kim, Yeni Lim, Soo-Yeon Park, You Jin Kim, Oran Kwon, Jin Hee Lee, Jae-Ho Shin, Yoon Kyoung Yang, Ji Yeon Kim

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food science and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Antithrombic effects ofFood science and biotechnology · 2025
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Leeseon Kim1Department of Food Science and Technology, Seoul National University of Science and Technology, Seoul, 01811 Republic of Korea.
Yeni Lim2Department of Nutritional Science and Food Management, Ewha Woman's University, Seoul, 03760 Republic of Korea.
Soo-Yeon Park2Department of Nutritional Science and Food Management, Ewha Woman's University, Seoul, 03760 Republic of Korea.
You Jin Kim2Department of Nutritional Science and Food Management, Ewha Woman's University, Seoul, 03760 Republic of Korea.
Oran Kwon2Department of Nutritional Science and Food Management, Ewha Woman's University, Seoul, 03760 Republic of Korea.
Jin Hee Lee3Department of Food Science and Biotechnology, CHA University, Seongnam, Gyeonggido 13488 Republic of Korea.
Jae-Ho Shin4Department of Biomedical Laboratory Science, Eulji University, Seongnam, Gyeonggido 13135 Republic of Korea.
Yoon Kyoung Yang5Department of Nutritional Science and Food Management, Soongeui Women's College, Seoul, 04628 Republic of Korea.
Ji Yeon Kim1Department of Food Science and Technology, Seoul National University of Science and Technology, Seoul, 01811 Republic of Korea.ORCID 0000-0002-4316-2726
Ewha Womans University · KRSeoul National University of Science and Technology · KRCHA University · KREulji University · KRSoongeui Women's College · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, garlic powder, tomato extract and a mixture of both were analyzed for anti-thrombotic effects using a collagen and epinephrine induced thrombosis model. Rats were randomly assigned to control, thrombosis induced control (COL/EP), garlic powder (G), tomato extract (T) and mixture of garlic powder and tomato extract (GT) groups. Test materials were administered for 7 days and thrombosis was induced by collagen and epinephrine injection. The results showed that G, T, and GT delayed activated partial thromboplastin time and reduced the expression of intracellular adhesion molecule-1 mRNA. Histological analysis of aorta and lung revealed that thrombosis was partially improved by G, T, and GT. Although there was no synergistic effect in GT compared to G and T treatment, this study showed that G, T, and GT have anti-thrombotic effect.

Indexed as

Activate partial thromboplastin timeAnti-thrombotic effectGarlicIntracellular adhesion molecule-1Mixture of garlic and tomatoTomato

Identifiers

PMID30319862
PMCPMC6170286
OpenAlexW2892308458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.