Evidence map›Paper›PMID 30319709›Full record

ArticleResearch in autism spectrum disorders2018

Treatment Utilization by Adults with Autism and Co-Occurring Anxiety or Depression.

Brenna B Maddox, Christina D Kang-Yi, Edward S Brodkin, David S Mandell

Abstract read
In one paragraph

Article in Research in autism spectrum disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Therapy and Antidepressant Use in 8- to 29-Year-Old Autistic Medicaid Enrollees With Depression.Autism : the international journal of research and practice · 2026
    Article
  3. Article
  4. Sensory Processing and Anxiety: Within and Beyond the Autism Spectrum.Current topics in behavioral neurosciences · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Psychedelic-Assisted Therapy for Social Adaptability in Autistic Adults.Current topics in behavioral neurosciences · 2022
    Article
  12. Health profiles of adults with autism spectrum disorder: Differences between women and men.Autism research : official journal of the International Society for Autism Research · 2021
    Article
  13. Article
  14. Prevalence of physical and mental health conditions in Medicare-enrolled, autistic older adults.Autism : the international journal of research and practice · 2020
    Article
  15. Is the Autism Boom Headed for Medicaid? Patterns in the Enrollment of Autistic Adults in Wisconsin Medicaid, 2008-2018.Autism research : official journal of the International Society for Autism Research · 2019
    Article
  16. Article
  17. A matter of time: The necessity of temporal language in research on health conditions that present with autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2019
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Brenna B MaddoxCenter for Mental Health Policy and Services Research, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania.
Christina D Kang-YiCenter for Mental Health Policy and Services Research, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania.
Edward S BrodkinCenter for Neurobiology and Behavior, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania.
David S MandellCenter for Mental Health Policy and Services Research, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania.
University of Pennsylvania · US

Funding

The Intellectual and Developmental Disabilities Research Center at CHOP/PennU54HD086984 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ABEL, EDWIN TED G. · 2016 to 2020
$6.3M
Improving Community Mental Health Services for Adults with ASD and Co-Occurring Psychiatric DisordersF32MH111166 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI MADDOX, BRENNA · 2017 to 2019
$187k
NICHD NIH HHS U54 HD086984NIMH NIH HHS F32 MH111166
6 · The paper itself

Abstract

backgroundWhile a growing body of research suggests that talk therapies can reduce anxiety and depression in adults with autism spectrum disorder (ASD), we know little about what community treatment for these disorders looks like for them. The present study investigated whether treatment utilization differs between adults with and without ASD who have anxiety or depression.

methodUsing Pennsylvania Medicaid claims data, adults aged 18-65 years diagnosed with ASD and depression or anxiety (n = 268) were matched 1:4 to adults with depression or anxiety disorder without ASD (n = 1,072). Chi-square tests and generalized linear models were used to estimate differences in diagnoses and psychiatric treatment between groups.

resultsWhile the proportion of people prescribed benzodiazepine and antidepressants did not differ between groups, the ASD group had more days per month prescribed for all medications. Adults with ASD also were more likely to be prescribed multiple medications concurrently and to use case management. Adults without ASD were more likely to receive talk therapy for anxiety/depression. Among those receiving talk therapy, adults with ASD averaged more individual visits per month.

conclusionsFindings suggest that therapists may need more session time for adults with ASD, although it is unclear if this time is dedicated to anxiety or depression treatment. The greater use of psychotropic medications among adults with ASD may suggest unresponsiveness to the talk therapy they receive or greater clinical complexity.

Indexed as

adultsanxietyAutism spectrum disorderdepressiontherapytreatment

Identifiers

PMID30319709
PMCPMC6181232
OpenAlexW2800437299

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.