Evidence map›Paper›PMID 30319662›Full record

ArticleFrontiers in immunology2018

Acute Myeloid Leukemia Cells Express ICOS Ligand to Promote the Expansion of Regulatory T Cells.

Yixiang Han, Yuqing Dong, Qianqian Yang, Wanling Xu, Songfu Jiang, Zhijie Yu, Kang Yu, Shenghui Zhang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05655000 (A First-in-Humans Supermicrosurgical Technique for the Neonatal Thymus Transplantation), which is not on this map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05655000 naunknown statusnot on this mapstarted 2022, after this paper: background citation

A First-in-Humans Supermicrosurgical Technique for the Neonatal Thymus Transplantation

TypeinterventionalSponsorFundacion Clinica Valle del LiliRan2022 to 2023Enrolled1ConditionsSafety IssuesArmsNeonatal thymus transplantation
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
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  10. Bone marrow immune cells and drug resistance in acute myeloid leukemia.Experimental biology and medicine (Maywood, N.J.) · 2025
    Review
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  12. Article
  13. Review
  14. Article
  15. Murine Regulatory CD4International journal of molecular sciences · 2024
    Article
  16. Review
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  18. Article
  19. Article
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yixiang HanCentral Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Yuqing DongDepartment of Hematology, Wenzhou Key Laboratory of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Qianqian YangDepartment of Hematology, Wenzhou Key Laboratory of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Wanling XuDepartment of Hematology, Wenzhou Key Laboratory of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Songfu JiangDepartment of Hematology, Wenzhou Key Laboratory of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Zhijie YuDepartment of Hematology, Wenzhou Key Laboratory of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Kang YuDepartment of Hematology, Wenzhou Key Laboratory of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Shenghui ZhangDepartment of Hematology, Wenzhou Key Laboratory of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
First Affiliated Hospital of Wenzhou Medical University · CNWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD4

Indexed as

AdolescentAdultAnimalsBiopsyBone MarrowCell Line, TumorCell ProliferationDisease-Free SurvivalDisease Models, AnimalFemaleGene Expression Regulation, NeoplasticHumansInducible T-Cell Co-Stimulator LigandInterleukin-10Leukemia, Myeloid, AcuteMaleICOSLG protein, humanIL10 protein, humanInducible T-Cell Co-Stimulator LigandInterleukin-10acute myeloid leukemiainducible T-cell costimulatorinducible T-cell costimulator ligandinterleukin-10regulatory T cells

Identifiers

PMID30319662
PMCPMC6168677
OpenAlexW2893372497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.