ArticleFrontiers in immunology2018
Effect of HTST and Holder Pasteurization on the Concentration of Immunoglobulins, Growth Factors, and Hormones in Donor Human Milk.
Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- The Breast Milk Immunoglobulinome.Nutrients · 2021Pooled it
- Trial
- Microbiological safety and immunoglobulin A retention in bottle-agitated Holder pasteurization of human milk.International breastfeeding journal · 2026Article
- Diurnal rhythms in melatonin and cortisol in very preterm human milk.Frontiers in nutrition · 2026Article
- EGF and IgA in maternal milk, donor milk, and milk fortifiers in the neonatal intensive care unit setting.PloS one · 2025Article
- Modeling ofInternational journal of food science · 2025Article
- The Early Appearance of Asthma and Its Relationship with Gut Microbiota: A Narrative Review.Microorganisms · 2024Review
- New alternatives to holder pasteurization in processing donor milk in human milk banks.Frontiers in nutrition · 2024Review
- High-Pressure Inactivation ofFoods (Basel, Switzerland) · 2023Article
- Human milk immune factors, maternal nutritional status, and infant sex: The INSPIRE study.American journal of human biology : the official journal of the Human Biology Council · 2023Article
- Article
- Impact of time-temperature combinations on the anti-Cytomegalovirus activity and biological components of human milk.Pediatric research · 2023Article
- Article
- Prevention of Chronic Morbidities in Extremely Premature Newborns with LISA-nCPAP Respiratory Therapy and Adjuvant Perinatal Strategies.Antioxidants (Basel, Switzerland) · 2023Review
- Neonatal Leptin Levels Predict the Early Childhood Developmental Assessment Scores of Preterm Infants.Nutrients · 2023Article
- Comparative analyses of holder pasteurization vs. HTST pasteurization for donor milk: a cost-minimization study applicable to human milk banks.International breastfeeding journal · 2023Article
- Insulin, Testosterone, and Albumin in Term and Preterm Breast Milk, Donor Milk, and Infant Formula.Nutrients · 2023Article
- Recommendations for the establishment and operation of a donor human milk bank.Nutrition reviews · 2023Article
- Effects of human donor milk on gut barrier function and inflammation:Frontiers in immunology · 2023Article
- The metabolome of human milk is altered differentially by Holder pasteurization and high hydrostatic pressure processing.Frontiers in nutrition · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Donor human milk (DHM) is submitted to Holder pasteurization (HoP) to ensure its microbiological safety in human milk banks but this treatment affects some of its bioactive compounds. The objective of this work was to compare the effects of HoP and high temperature short time (HTST) treatments on some bioactive compounds found in DHM. A total of 24 DHM batches were processed in a continuous HTST system (70, 72, and 75°C for 5-25 s) and by HoP (62.5°C for 30 min). The concentrations of immunoglobulins (Igs) A, G, and M, transforming growth factor-beta 2 (TGF-β
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.