Evidence map›Paper›PMID 30319658›Full record

ReviewFrontiers in immunology2018

Gut Mucosal Antibody Responses and Implications for Food Allergy.

Ramona A Hoh, Scott D Boyd

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Local immunoglobulin production in nasal tissues: A key to pathogenesis in chronic rhinosinusitis with nasal polyps and aspirin-exacerbated respiratory disease.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ramona A HohDepartment of Pathology, Stanford University, Stanford, CA, United States.
Scott D BoydDepartment of Pathology, Stanford University, Stanford, CA, United States.

Funding

UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORIR01AI025567 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOBLEY, HARRY L. · 1989 to 2008
$2.2M
NIAID NIH HHS R01 AI025567
6 · The paper itself

Abstract

The gastrointestinal mucosa is a critical environmental interface where plasma cells and B cells are exposed to orally-ingested antigens such as food allergen proteins. It is unclear how the development of B cells and plasma cells in the gastrointestinal mucosa differs between healthy humans and those with food allergy, and how B cells contribute to, or are affected by, the breakdown of oral tolerance. In particular, the antibody gene repertoires associated with symptomatic allergy have only begun to be characterized in full molecular detail. Here, we review literature concerning B cells and plasma cells in the gastrointestinal system in the context of food allergy, with a focus on human studies.

Indexed as

AllergensAnimalsB-LymphocytesDisease Models, AnimalFoodFood HypersensitivityGastric MucosaHumansImmune ToleranceImmunoglobulin EIntestinal MucosaAllergensImmunoglobulin Eantibody repertoireB cellfood allergygastrointestinal mucosaIgEmemoryplasma cell

Identifiers

PMID30319658
PMCPMC6170638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.