Evidence map›Paper›PMID 30319650›Full record

ReviewFrontiers in immunology2018

IL-22: An Underestimated Player in Natural Resistance to Tuberculosis?

Katharina Ronacher, Roma Sinha, Michelle Cestari

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Crosstalk betweenFrontiers in immunology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. A Series of 35 Cutaneous Infections Caused byJournal of tropical medicine · 2023
    Article
  16. Characterization ofJournal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  17. Article
  18. Article
  19. Cytokine Receptors-Regulators of Antimycobacterial Immune Response.International journal of molecular sciences · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Katharina RonacherDivision of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, SAMRC Centre for Tuberculosis Research, DST-NRF Centre of Excellence for Biomedical Tuberculosis Research, Stellenbosch University, Cape Town, South Africa.
Roma SinhaInfection, Immunity and Metabolism Group, Translational Research Institute, Mater Research Institute and The University of Queensland, Brisbane, QLD, Australia.
Michelle CestariInfection, Immunity and Metabolism Group, Translational Research Institute, Mater Research Institute and The University of Queensland, Brisbane, QLD, Australia.
Mater Research · AUStellenbosch University · ZAUniversity of Queensland · AU

Funding

Altered immune-endocrine axis in type 2 diabetes and tuberculosis riskR01AI116039 · NIAID · STELLENBOSCH UNIVERSITY · PI KLEYNHANS, LEANIE, RESTREPO, BLANCA I · 2015 to 2019
$1.7M
NIAID NIH HHS R01 AI116039
6 · The paper itself

Abstract

Approximately 10% of individuals latently infected with

Indexed as

AnimalsDisease Models, AnimalDisease ResistanceEpithelial CellsHumansInterleukin-22InterleukinsKiller Cells, NaturalLatent TuberculosisLungLymphocyte ActivationMacrophagesMycobacterium tuberculosisReceptors, InterleukinRespiratory MucosaT-Lymphocytes, Helper-InducerInterleukin-22interleukin-22 receptorInterleukinsReceptors, InterleukinIL-22R1interleukin-22Mycobacterium tuberculosisrespiratory infectionsT lymphocytestuberculosis

Identifiers

PMID30319650
PMCPMC6167461
OpenAlexW2893721464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.