Evidence map›Paper›PMID 30319629›Full record

ReviewFrontiers in immunology2018

Determination of T Follicular Helper Cell Fate by Dendritic Cells.

Jayendra Kumar Krishnaswamy, Samuel Alsén, Ulf Yrlid, Stephanie C Eisenbarth, Adam Williams

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026
    Review
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  9. Immunostimulatory Pickering emulsion for oral vaccine delivery.International journal of pharmaceutics · 2025
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jayendra Kumar KrishnaswamyBioscience, Respiratory, Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
Samuel AlsénDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ulf YrlidDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Stephanie C EisenbarthDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, United States.
Adam WilliamsThe Jackson Laboratory for Genomic Medicine, Farmington, CT, United States.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Regulation of adaptive immunity by the NOD-like receptor NLRP10R01AI108829 · NIAID · YALE UNIVERSITY · PI EISENBARTH, STEPHANIE CAROLINE · 2014 to 2018
$2.1M
The Function of lncRNAs in Airway Epithelial CellsR21AI133440 · NIAID · JACKSON LABORATORY · PI WILLIAMS, ADAM · 2018 to 2019
$520k
The Role of the lncRNA MORRBID in Controlling Dendritic Cell Lifespan and Adaptive ImmunityR21AI135221 · NIAID · JACKSON LABORATORY · PI WILLIAMS, ADAM · 2018 to 2019
$520k
NCATS NIH HHS UL1 TR001863NIAID NIH HHS R01 AI108829NIAID NIH HHS R21 AI133440NIAID NIH HHS R21 AI135221
6 · The paper itself

Abstract

T follicular helper (Tfh) cells are a specialized subset of CD4

Indexed as

AnimalsAntigen PresentationB-LymphocytesCell DifferentiationDendritic CellsHumansImmunity, HumoralLymph NodesLymphocyte ActivationT-Lymphocytes, Helper-InducerDC migrationDC subsetdendritic cellhumoral responseTfh cellvaccine

Identifiers

PMID30319629
PMCPMC6170619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.