Evidence map›Paper›PMID 30319609›Full record

ArticleFrontiers in immunology2018

Acetylcholine Inhibits Monomeric C-Reactive Protein Induced Inflammation, Endothelial Cell Adhesion, and Platelet Aggregation; A Potential Therapeutic?

Mark Slevin, Rocco S Iemma, Yasmin Zeinolabediny, Donghui Liu, Glenn R Ferris, Vittorio Caprio, Nicola Phillips, Mario Di Napoli, Baoqiang Guo, Xianwei Zeng and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  5. Review
  6. Editorial: COVID-19 and thrombo-inflammatory responses.Frontiers in cardiovascular medicine · 2023
    Article
  7. Article
  8. Review
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 5 countries.

Mark SlevinFaculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Rocco S IemmaFaculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Yasmin ZeinolabedinyFaculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Donghui LiuFaculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Glenn R FerrisFaculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Vittorio CaprioFaculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Nicola PhillipsFaculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Mario Di NapoliNeurological Service, Ospedale San Camillo de Lellis, Rieti, Italy.
Baoqiang GuoFaculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Xianwei ZengInstitute of Dementia and Neurolgical Aging, Weifang Medical University, Weifang, China.
Raid AlBaradieApplied Medical Sciences College, Majmaah University, Al Majma'ah, Saudi Arabia.
Naif K BinsalehFaculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Garry McDowellFaculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Wen-Hui FangFaculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Manchester Metropolitan University · GBMajmaah University · SAOspedale generale di zona San Camillo Treviso · ITUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · ROWeifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcetylcholineCell AdhesionC-Reactive ProteinEndothelial CellsHumansInflammationMAP Kinase Signaling SystemMonocytesNicotinePhosphorylationPlatelet AggregationPlatelet Function TestsTacrineU937 CellsAcetylcholineC-Reactive ProteinNicotineTacrineacetylcholinecell adhesionCRPinflammationnicotine

Identifiers

PMID30319609
PMCPMC6168760
OpenAlexW2893461430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.