Evidence map›Paper›PMID 30319603›Full record

ArticleFrontiers in immunology2018

Polyphyllin I Ameliorates Collagen-Induced Arthritis by Suppressing the Inflammation Response in Macrophages Through the NF-κB Pathway.

Qiong Wang, Xin Zhou, Yongjian Zhao, Jun Xiao, Yao Lu, Qi Shi, Yongjun Wang, Hongyan Wang, Qianqian Liang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 104 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. [Puerarin alleviates rheumatoid arthritis in rats by modulating TAK1-mediated TLR4/NF-κB signaling pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Prognostic value ofFrontiers in cardiovascular medicine · 2025
    Article
  11. Article
  12. Resolution of inflammation during rheumatoid arthritis.Frontiers in cell and developmental biology · 2025
    Review
  13. Review
  14. Review
  15. Article
  16. The role ofHeliyon · 2024
    Review
  17. Article
  18. Article
  19. Saponins ofMolecules (Basel, Switzerland) · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Qiong WangLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xin ZhouState Key Laboratory of Cell Biology, Key Laboratory of Systems Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Innovation Center for Cell Signaling Network, Shanghai, China.
Yongjian ZhaoLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jun XiaoState Key Laboratory of Cell Biology, Key Laboratory of Systems Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Innovation Center for Cell Signaling Network, Shanghai, China.
Yao LuState Key Laboratory of Cell Biology, Key Laboratory of Systems Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Innovation Center for Cell Signaling Network, Shanghai, China.
Qi ShiLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yongjun WangLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hongyan WangState Key Laboratory of Cell Biology, Key Laboratory of Systems Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Innovation Center for Cell Signaling Network, Shanghai, China.
Qianqian LiangLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Shanghai University of Traditional Chinese Medicine · CNUniversity of Chinese Academy of Sciences · CNLonghua Hospital Shanghai University of Traditional Chinese Medicine · CNCenter for Excellence in Molecular Cell Science · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnkle JointArthritis, ExperimentalArthritis, RheumatoidCollagen Type IIDiosgeninFemaleHEK293 CellsHumansI-kappa B KinaseInflammation MediatorsInterferon-gammaLipopolysaccharidesMacrophagesMiceMice, Inbred C57BLChuk protein, mouseCollagen Type IIDiosgeninI-kappa B KinaseIkbkb protein, mouseInflammation MediatorsInterferon-gammaLipopolysaccharidespolyphyllin IRela protein, mouseRNA, Small InterferingTranscription Factor RelAcollagen-induced arthritisinflammationNF-κBpolyphyllin Iprimary macrophages

Identifiers

PMID30319603
PMCPMC6170622
OpenAlexW2892913867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.