Evidence map›Paper›PMID 30319555›Full record

ArticleFrontiers in microbiology2018

Quorum Sensing Modulates the Epibiotic-Parasitic Relationship Between

Joseph K Bedree, Batbileg Bor, Lujia Cen, Anna Edlund, Renate Lux, Jeffrey S McLean, Wenyuan Shi, Xuesong He

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 50 citations in OpenAlex.

  1. Oral Actinobacteria sense and defend against parasitic epibionts.bioRxiv : the preprint server for biology · 2026
    Article
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  6. Identifying essential genes inJournal of bacteriology · 2025
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  12. Three's a crowd: Saccharibacteria episymbiosis modulates phage predation of host bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Joseph K BedreeSection of Oral Biology, Division of Oral Biology and Medicine, School of Dentistry, University of California, Los Angeles, Los Angeles, CA, United States.
Batbileg BorDepartment of Microbiology, The Forsyth Institute, Cambridge, MA, United States.
Lujia CenDepartment of Microbiology, The Forsyth Institute, Cambridge, MA, United States.
Anna EdlundDepartment of Genomic Medicine, J. Craig Venter Institute, La Jolla, CA, United States.
Renate LuxSection of Periodontics, Division of Constitutive and Regenerative Sciences, School of Dentistry, University of California, Los Angeles, Los Angeles, CA, United States.
Jeffrey S McLeanDepartment of Periodontics, School of Dentistry, University of Washington, Seattle, WA, United States.
Wenyuan ShiDepartment of Microbiology, The Forsyth Institute, Cambridge, MA, United States.
Xuesong HeDepartment of Microbiology, The Forsyth Institute, Cambridge, MA, United States.
University of California, Los Angeles · USJ. Craig Venter Institute · USUniversity of Washington · US

Funding

Domestication and characterization of TM7-the most elusive oral phylumR01DE023810 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Xuesong He, Jeffrey Scott McLean · 2014 to 2026
$6.6M
Making a quantum leap in plaque research with modern sciencesR01DE020102 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HE, XUESONG, MCLEAN, JEFFREY SCOTT · 2010 to 2020
$3.7M
Studying the Protective Effects of Normal Oral FloraR01DE026186 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HE, XUESONG, MCLEAN, JEFFREY SCOTT · 2016 to 2020
$2.1M
Molecular and pathogenic study of an oral TM7 strain, the first cultivated ultra-small bacteriumR00DE027719 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI BOR, BATBILEG · 2020 to 2022
$747k
Molecular and pathogenic study of an oral TM7 strain, the first cultivated ultra-small bacteriumK99DE027719 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI BOR, BATBILEG · 2018 to 2019
$268k
Shedding Light on Microbial Dark MatterF31DE026057 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEDREE, JOSEPH KERNAN · 2016 to 2020
$156k
NIDCR NIH HHS F31 DE026057NIDCR NIH HHS K99 DE027719NIDCR NIH HHS R00 DE027719NIDCR NIH HHS R01 DE020102NIDCR NIH HHS R01 DE023810NIDCR NIH HHS R01 DE026186
6 · The paper itself

Abstract

The ultra-small, obligate parasitic epibiont, TM7x, the first and only current member of the long-elusive Saccharibacteria (formerly the TM7 phylum) phylum to be cultivated, was isolated in co-culture with its bacterial host,

Indexed as

Actinomycesepibionthuman-associatedinterspecies interactionoral microbiomeTM7

Identifiers

PMID30319555
PMCPMC6166536
OpenAlexW2893848567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.