Evidence map›Paper›PMID 30319400›Full record

ArticleFrontiers in pharmacology2018

Metronomic Four-Drug Regimen Has Anti-tumor Activity in Pediatric Low-Grade Glioma; The Results of a Phase II Clinical Trial.

Arnauld Verschuur, Marie-Amélie Heng-Maillard, Philippe Dory-Lautrec, Romain Truillet, Elisabeth Jouve, Pascal Chastagner, Pierre Leblond, Isabelle Aerts, Stéphane Honoré, Natasha Entz-Werle and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Chemotherapy in pediatric low-grade gliomas (PLGG).Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

Arnauld VerschuurDepartment of Pediatric Oncology, La Timone Children's Hospital, Assistance Publique Hôpitaux de Marseille, Marseille, France.
Marie-Amélie Heng-MaillardDepartment of Pediatric Oncology, La Timone Children's Hospital, Assistance Publique Hôpitaux de Marseille, Marseille, France.
Philippe Dory-LautrecDepartment of Neuroradiology, La Timone Hospital, Assistance Publique Hôpitaux de Marseille, Marseille, France.
Romain TruilletCIC-CPCET, La Timone Hospital, Assistance Publique Hôpitaux de Marseille, Marseille, France.
Elisabeth JouveCIC-CPCET, La Timone Hospital, Assistance Publique Hôpitaux de Marseille, Marseille, France.
Pascal ChastagnerDepartment of Pediatric Oncology, Children's Hospital, Nancy, France.
Pierre LeblondPediatric Oncology Unit, Oscar Lambret Centre, Lille, France.
Isabelle AertsPediatric Department, Institut Curie, Paris, France.
Stéphane HonoréDepartment of Clinical Pharmacy, La Timone Hospital, Assistance Publique Hôpitaux de Marseille, Marseille, France.
Natasha Entz-WerlePédiatrie Onco-Hématologie, CHU Hautepierre, Strasbourg, France.
Nicolas SirventDepartment of Pediatric and Adolescent Hematology-Oncology, Children's Hospital Arnaud de Villeneuve, Montpellier, France.
Jean-Claude GentetDepartment of Pediatric Oncology, La Timone Children's Hospital, Assistance Publique Hôpitaux de Marseille, Marseille, France.
Nadège CorradiniDepartment of Pediatric and Adolescent Hematology-Oncology, Hôpital Mère-Enfant, Nantes, France.
Nicolas AndréDepartment of Pediatric Oncology, La Timone Children's Hospital, Assistance Publique Hôpitaux de Marseille, Marseille, France.
Assistance Publique Hôpitaux de Marseille · FRHôpital de la Timone · FRCentre de Recherche en Cancérologie de Marseille · FRCentre Hospitalier Régional et Universitaire de Nancy · FRCentre Oscar Lambret · FRHôpital Arnaud de Villeneuve · FRHôpital d'Hautepierre · FRHôpital Mère-Enfant · FRInstitut Curie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

angiogenesisdrug repositioningimmunitylow grade gliomametronomic chemotherapypediatric oncology

Identifiers

PMID30319400
PMCPMC6171442
OpenAlexW2893808205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.