Evidence map›Paper›PMID 30319373›Full record

ArticleFrontiers in human neuroscience2018

Smoking Cessation With 20 Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Applied to Two Brain Regions: A Pilot Study.

Da Chang, Jian Zhang, Wei Peng, Zhuowen Shen, Xin Gao, Youhong Du, Qiu Ge, Donghui Song, Yuanqi Shang, Ze Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in human neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Comparing neuromodulation targets to reduce cigarette craving and withdrawal: a randomized clinical trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
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  15. The effects of intermittent theta burst stimulation (iTBS) on resting-state brain entropy (BEN).Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
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  17. Resting state fMRI-based temporal coherence mapping.Imaging neuroscience (Cambridge, Mass.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Da ChangDepartment of Psychology, Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China.
Jian ZhangDepartment of Psychology, Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China.
Wei PengDepartment of Psychology, Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China.
Zhuowen ShenDepartment of Psychology, Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China.
Xin GaoDepartment of Psychology, Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China.
Youhong DuDepartment of Psychology, Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China.
Qiu GeDepartment of Psychology, Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China.
Donghui SongDepartment of Psychology, Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China.
Yuanqi ShangDepartment of Psychology, Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China.
Ze WangDepartment of Psychology, Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China.
Hangzhou Normal University · CNTemple University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic smoking impairs brain functions in the prefrontal cortex and the projecting meso-cortical limbic system. The purpose of this pilot study is to examine whether modulating the frontal brain activity using high-frequency repetitive transcranial magnetic stimulation (rTMS) can improve smoking cessation and to explore the changing pattern of the brain activity after treatment. Fourteen treatment-seeking smokers were offered a program involving 10 days of rTMS treatment with a follow-up for another 25 days. A frequency of 20 Hz rTMS was sequentially applied on the left dorso-lateral prefrontal cortex (DLPFC) and the superior medial frontal cortex (SMFC). The carbon monoxide (CO) level, withdrawal, craving scales, and neuroimaging data were collected. Ten smokers completed the entire treatment program, and 90% of them did not smoke during the 25-day follow-up time. A significant smoking craving reduction and resting brain activity reduction measured by the cerebral blood flow (CBF) and brain entropy (BEN) were observed after 10 days of 20 Hz rTMS treatments compared to the baseline. Although limited by sample size, these pilot findings definitely showed a high potential of multiple-target high-frequency rTMS in smoking cessation and the utility of fMRI for objectively assessing the treatment effects.

Indexed as

brain entropycerebral blood flowleft dorso-lateral prefrontal cortexrepetitive transcranial magnetic stimulationsmoking cessationsuperior medial frontal cortex

Identifiers

PMID30319373
PMCPMC6166007
OpenAlexW2892647046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.