Evidence map›Paper›PMID 30319343›Full record

ArticleFrontiers in neuroscience2018

Parameters of Surface Electromyogram Suggest That Dry Immersion Relieves Motor Symptoms in Patients With Parkinsonism.

German G Miroshnichenko, Alexander Yu Meigal, Irina V Saenko, Liudmila I Gerasimova-Meigal, Liudmila A Chernikova, Natalia S Subbotina, Saara M Rissanen, Pasi A Karjalainen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

German G MiroshnichenkoBiosignal Analysis and Medical Imaging Group, Department of Applied Physics, Faculty of Science and Forestry, University of Eastern Finland, Kuopio, Finland.
Alexander Yu MeigalLaboratory for Novel Methods in Physiology, Institute of High-Tech Biomedical Solutions, Petrozavodsk State University, Petrozavodsk, Russia.
Irina V SaenkoLaboratory of Gravitational Physiology of Sensorimotor System, Department of Sensorimotor Physiology and Countermeasure, Institute of BioMedical Problems, Russian Academy of Sciences, Moscow, Russia.
Liudmila I Gerasimova-MeigalDepartment of Human and Animal Physiology, Physiopathology, Histology, Petrozavodsk State University, Petrozavodsk, Russia.
Liudmila A ChernikovaDepartment of Neurorehabilitation and Physiotherapy, Research Center of Neurology, Russian Academy of Medical Sciences, Moscow, Russia.
Natalia S SubbotinaDepartment of Neurology, Psychiatry, and Microbiology, Petrozavodsk State University, Petrozavodsk, Russia.
Saara M RissanenBiosignal Analysis and Medical Imaging Group, Department of Applied Physics, Faculty of Science and Forestry, University of Eastern Finland, Kuopio, Finland.
Pasi A KarjalainenBiosignal Analysis and Medical Imaging Group, Department of Applied Physics, Faculty of Science and Forestry, University of Eastern Finland, Kuopio, Finland.
Petrozavodsk State University · RUUniversity of Eastern Finland · FIInstitute of Biomedical Problems · RUResearch Center of Neurology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dry immersion (DI) is acknowledged as a reliable space flight analog condition. At DI, subject is immersed in water being wrapped in a waterproof film to imitate microgravity (μG). Microgravity is known to decrease muscle tone due to deprivation of the sensory stimuli that activate the reflexes that keep up the muscle tone. In contrary, parkinsonian patients are characterized by elevated muscle tone, or rigidity, along with rest tremor and akinesia. We hypothesized that DI can diminish the elevated muscle tone and/or the tremor in parkinsonian patients. Fourteen patients with Parkinson's disease (PD, 10 males, 4 females, 47-73 years) and 5 patients with vascular parkinsonism (VP, 1 male, 4 females, 65-72 years) participated in the study. To evaluate the effect of DI on muscles' functioning, we compared parameters of surface electromyogram (sEMG) measured before and after a single 45-min long immersion session. The sEMG recordings were made from the biceps brachii muscle, bilaterally. Each recording was repeated with the following loading conditions: with arms hanging freely down, and with 0, 1, and 2 kg loading on each hand with elbows flexed to 90°. The sEMG parameters comprised of amplitude, median frequency, time of decay of mutual information, sample entropy, correlation dimension, recurrence rate, and determinism of sEMG. These parameters have earlier been proved to be sensitive to PD severity. We used the Wilcoxon test to decide which parameters were statistically significantly different before and after the dry immersion. Accepting the

Indexed as

auto-mutual informationdeterminismdry immersionelectromyogrammicrogravitynonlinear dynamicsparkinsonismrehabilitation

Identifiers

PMID30319343
PMCPMC6168649
OpenAlexW2889850831

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.