Evidence map›Paper›PMID 30319253›Full record

ArticleInternational journal of nanomedicine2018

Fluorescence properties of curcumin-loaded nanoparticles for cell tracking.

Bassam Felipe Mogharbel, Julio Cesar Francisco, Ana Carolina Irioda, Dilcele Silva Moreira Dziedzic, Priscila Elias Ferreira, Daiany de Souza, Carolina Maria Costa Oliveira de Souza, Nelson Bergonse Neto, Luiz Cesar Guarita-Souza, Celia Regina Cavichiolo Franco and 9 more

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
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  3. Peripheral nerve repair: innovations and future directions.Journal of translational medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Bassam Felipe MogharbelCell Therapy and Biotechnology in Regenerative Medicine Department, Pelé Pequeno Príncipe Institute, Child and Adolescent Health Research and Pequeno Príncipe Faculty, Curitiba, Paraná, Brazil, katherinecarv@gmail.com.
Julio Cesar FranciscoCell Therapy and Biotechnology in Regenerative Medicine Department, Pelé Pequeno Príncipe Institute, Child and Adolescent Health Research and Pequeno Príncipe Faculty, Curitiba, Paraná, Brazil, katherinecarv@gmail.com.
Ana Carolina IriodaCell Therapy and Biotechnology in Regenerative Medicine Department, Pelé Pequeno Príncipe Institute, Child and Adolescent Health Research and Pequeno Príncipe Faculty, Curitiba, Paraná, Brazil, katherinecarv@gmail.com.
Dilcele Silva Moreira DziedzicCell Therapy and Biotechnology in Regenerative Medicine Department, Pelé Pequeno Príncipe Institute, Child and Adolescent Health Research and Pequeno Príncipe Faculty, Curitiba, Paraná, Brazil, katherinecarv@gmail.com.
Priscila Elias FerreiraCell Therapy and Biotechnology in Regenerative Medicine Department, Pelé Pequeno Príncipe Institute, Child and Adolescent Health Research and Pequeno Príncipe Faculty, Curitiba, Paraná, Brazil, katherinecarv@gmail.com.
Daiany de SouzaCell Therapy and Biotechnology in Regenerative Medicine Department, Pelé Pequeno Príncipe Institute, Child and Adolescent Health Research and Pequeno Príncipe Faculty, Curitiba, Paraná, Brazil, katherinecarv@gmail.com.
Carolina Maria Costa Oliveira de SouzaCell Therapy and Biotechnology in Regenerative Medicine Department, Pelé Pequeno Príncipe Institute, Child and Adolescent Health Research and Pequeno Príncipe Faculty, Curitiba, Paraná, Brazil, katherinecarv@gmail.com.
Nelson Bergonse NetoInstitute of Biological and Health Sciences, Pontifical Catholic University of Paraná (PUCPR), Centro de Ciências Biológicas e da Saúde (CCBS), Curitiba, Brazil.
Luiz Cesar Guarita-SouzaInstitute of Biological and Health Sciences, Pontifical Catholic University of Paraná (PUCPR), Centro de Ciências Biológicas e da Saúde (CCBS), Curitiba, Brazil.
Celia Regina Cavichiolo FrancoCell Biology Department, Federal University of Paraná, Curitiba, Paraná, Brazil.
Celso Vataru NakamuraDepartment of Pharmaceutical Sciences, Universidade Estadual de Maringá, Maringá, Paraná, Brazil.
Vanessa KaplumDepartment of Pharmaceutical Sciences, Universidade Estadual de Maringá, Maringá, Paraná, Brazil.
Letícia MazzarinoDepartment of Pharmaceutical Sciences, NanoBioMat Laboratory, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Elenara Lemos-SennaDepartment of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Redouane BorsaliCentre de Recherches sur les Macromolécules Végétales (CERMAV), Centre National de la Recherche Scientifique (CNRS), University Grenoble Alpes, F-38000, Grenoble, France.
Paula A SotoInstituto de Química y Físicoquímica Biológica (IQUIFIB), Departament of Química Biológica, Facultad de Farmacia y Bíoquímica, Universidad de Buenos Aires (UBA) Consejo nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentine.
Patricia Setton-AvrujInstituto de Química y Físicoquímica Biológica (IQUIFIB), Departament of Química Biológica, Facultad de Farmacia y Bíoquímica, Universidad de Buenos Aires (UBA) Consejo nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentine.
Eltyeb AbdelwahidFeinberg School of Medicine, Feinberg Cardiovascular Research Institute, Northwestern University, Chicago, Il, USA.
Katherine Athayde Teixeira de CarvalhoCell Therapy and Biotechnology in Regenerative Medicine Department, Pelé Pequeno Príncipe Institute, Child and Adolescent Health Research and Pequeno Príncipe Faculty, Curitiba, Paraná, Brazil, katherinecarv@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPosttransplant cell tracking, via stem cell labeling, is a crucial strategy for monitoring and maximizing benefits of cell-based therapies. The structures and functionalities of polysaccharides, proteins, and lipids allow their utilization in nanotechnology systems. MATERIALS AND

methodsIn the present study, we analyzed the potential benefit of curcumin-loaded nanoparticles (NPC) using Vero cells (in vitro) and NPC-labeled adipose-derived mesenchymal stem cells (NPC-ADMSCs) (in vivo) in myocardial infarction and sciatic nerve crush preclinical models. Thereafter, transplantation, histological examination, real time imaging, and assessment of tissue regeneration were done.

resultsTransplanted NPC-ADMSCs were clearly identified and revealed potential benefit when used in cell tracking.

conclusionThis approach may have broad applications in modeling labeled transplanted cells and in developing improved stem cell therapeutic strategies.

Indexed as

AnimalsCell DifferentiationCell TrackingChlorocebus aethiopsCurcuminFluorescenceGreen Fluorescent ProteinsImmunophenotypingMesenchymal Stem CellsMesenchymal Stem Cell TransplantationMyocardial InfarctionNanoparticlesNerve CrushRats, WistarSciatic NerveVero CellsCurcuminGreen Fluorescent Proteinscell markingmesenchymal stem cellsmyocardium infarctionsciatic nerve crushtransplantation

Identifiers

PMID30319253
PMCPMC6168007

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.