Evidence map›Paper›PMID 30319189›Full record

ArticleIndian journal of clinical biochemistry : IJCB2018

Association of Vitamin D Receptor (FokI and BsmI) Gene Polymorphism with Bone Mineral Density and Their Effect on 25-Hydroxyvitamin D Level in North Indian Postmenopausal Women with Osteoporosis.

Israr Ahmad, Tabrez Jafar, Farzana Mahdi, Md Arshad, Siddharth Kumar Das, Shah Waliullah, Abbas Ali Mahdi

Open access · bronzeAbstract read
In one paragraph

Article in Indian journal of clinical biochemistry : IJCB, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Israr Ahmad1Department of Biochemistry, King George's Medical University, Lucknow, 226003 India.
Tabrez Jafar3Department of Zoology, Lucknow University, Lucknow, 226007 India.
Farzana Mahdi2Department of Biochemistry, Era's Lucknow Medical College and Hospital, Lucknow, 226003 India.
Md Arshad3Department of Zoology, Lucknow University, Lucknow, 226007 India.
Siddharth Kumar Das4Department of Rheumatology, King George's Medical University, Lucknow, 226003 India.
Shah Waliullah5Department of Orthopedic Surgery, King George's Medical University, Lucknow, 226003 India.
Abbas Ali Mahdi1Department of Biochemistry, King George's Medical University, Lucknow, 226003 India.
King George's Medical University · INUniversity of Lucknow · INEra's Lucknow Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is a systemic disease with a strong genetic component. Vitamin D receptor (VDR) has been suggested as a candidate gene for osteoporosis. Therefore the present study was aimed to investigate the pattern of allelic variants of VDR gene polymorphism (FokI and BsmI), its influence on vitamin D levels and bone mineral density (BMD) in North Indian postmenopausal women with osteoporosis for possible genetic association. 254 postmenopausal osteoporotic women and 254 postmenopausal non osteoporotic women were included in the study. VDR FokI and BsmI gene polymorphism gene were assessed by the PCR-RFLP method. Serum 25-hydroxyvitamin D was measured by the ELISA. BMD at the L

Indexed as

Bone mineral densityOsteoporosisPolymorphismPostmenopausal womenVitamin D receptor

Identifiers

PMID30319189
PMCPMC6170232
OpenAlexW2766377974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.