ArticleIndian journal of clinical biochemistry : IJCB2018
Thiamine Deficiency Induced Dietary Disparity Promotes Oxidative Stress and Neurodegeneration.
Article in Indian journal of clinical biochemistry : IJCB, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Vitamin B1 and sepsis: a prospective single-center study.Frontiers in nutrition · 2026Article
- Protective Role of Thiamine Pyrophosphate Against Erlotinib-Induced Oxidative and Inflammatory Damage in Rat Optic Nerve.Biomedicines · 2025Article
- Thiamine (Vitamin B1)-An Essential Health Regulator.Nutrients · 2025Review
- Evaluating the link between the dietary intake of vitamin B and constipation: a population-based study.Frontiers in nutrition · 2025Article
- The association between dietary vitamin B1 intake and constipation: a population-based study.BMC gastroenterology · 2024Article
- The role of dietary antioxidants in type 2 diabetes and neurodegenerative disorders: An assessment of the benefit profile.Heliyon · 2023Review
- Follow-up of the re-evaluation of sulfur dioxide (E 220), sodium sulfite (E 221), sodium bisulfite (E 222), sodium metabisulfite (E 223), potassium metabisulfite (E 224), calcium sulfite (E 226), calcium bisulfite (E 227) and potassium bisulfite (E 228).EFSA journal. European Food Safety Authority · 2022Article
- High Lipid Content of Prey Fish andBiomolecules · 2022Article
- Protective effects of thiamine onFrontiers in microbiology · 2022Article
- Clinical Characteristics of Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes.Life (Basel, Switzerland) · 2021Review
- Review
- Protective Role of Vitamin BFrontiers in physiology · 2021Article
- Supplemental thiamine as a practical, potential way to prevent Alzheimer's disease from commencing.Alzheimer's & dementia (New York, N. Y.) · 2021Article
- Monitoring the Diversity and Metabolic Shift of Gut Microbes during Green Tea Feeding in an In Vitro Human Colonic Model.Molecules (Basel, Switzerland) · 2020Article
- Thiamine-Responsive Acute Pulmonary Hypertension of Early Infancy (TRAPHEI)-A Case Series and Clinical Review.Children (Basel, Switzerland) · 2020Review
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thiamine or vitamin B1 is a well known coenzyme and nutrient necessary for the assembly and right functioning of several enzymes involved in the energy metabolism. The present study evaluates oxidative stress and prevalence of neurodegenerative conditions in the brain following TD. The study was carried out on mice (Musmusculus) in three groups, namely control and thiamine-deficient group for 8 (TD 8) and 10 (TD 10) days. Lipid peroxidation was determined in terms of reduced glutathione (GSH) and thiobarbituric acid reactive substance (TBARS). The level of antioxidant enzymes such as catalase (CAT), glutathione reductase, glutathione peroxidase (GPx), superoxide dismutase (SOD) and glutathione transferase (GST) were measured along with histopathological studies in all the groups. There was significant increase in the TBARS levels in group II (TD 8) and group III (TD 10) animals in comparison to controls (Group I). The GSH levels were found to be lower in both the treated groups. The level of antioxidant enzymes CAT (
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