Evidence map›Paper›PMID 30319072›Full record

ArticleThyroid : official journal of the American Thyroid Association2018

Molecular Classification of Thyroid Nodules with Indeterminate Cytology: Development and Validation of a Highly Sensitive and Specific New miRNA-Based Classifier Test Using Fine-Needle Aspiration Smear Slides.

Marcos Tadeu Dos Santos, Ana Lígia Buzolin, Ricardo Ribeiro Gama, Eduardo Caetano Albino da Silva, Rozany Mucha Dufloth, David Livingstone Alves Figueiredo, André Lopes Carvalho

Open access · hybridAbstract readValidation Study
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
  5. Review
  6. Article
  7. CouldDiagnostics (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Molecular testing for thyroid nodules: Where are we now?Reviews in endocrine & metabolic disorders · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. High Diagnostic Accuracy of Epigenetic Imprinting Biomarkers in Thyroid Nodules.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Article
  15. Review
  16. Reference Genes for qPCR-Based miRNA Expression Profiling in 14 Human Tissues.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Marcos Tadeu Dos SantosDepartment of Research and Development, Onkos Molecular Diagnostics, Ribeirão Preto/SP, Brazil.
Ana Lígia BuzolinDepartment of Research and Development, Onkos Molecular Diagnostics, Ribeirão Preto/SP, Brazil.
Ricardo Ribeiro GamaDepartment of Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos/SP, Brazil.
Eduardo Caetano Albino da SilvaDepartment of Pathology, Barretos Cancer Hospital, Barretos/SP, Brazil.
Rozany Mucha DuflothDepartment of Pathology, Barretos Cancer Hospital, Barretos/SP, Brazil.
David Livingstone Alves FigueiredoMidwestern State University (UNICENTRO), Guarapuava/PR, Brazil.
André Lopes CarvalhoDepartment of Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos/SP, Brazil.
Hospital de Câncer de Barretos · BRClinics Hospital of Ribeirão Preto · BRUniversidade Estadual do Centro-Oeste · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAlgorithmsBiopsy, Fine-NeedleFemaleHumansMaleMicroRNAsMiddle AgedRetrospective StudiesSensitivity and SpecificityThyroid NoduleMicroRNAsindeterminate thyroid nodulemiRNAmolecular classifiermolecular diagnosticsprecision endocrinology

Identifiers

PMID30319072
PMCPMC6308280
OpenAlexW2896208207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.