Evidence map›Paper›PMID 30318985›Full record

ReviewThe Journal of hand surgery, European volume2019

A multidisciplinary review of triphalangeal thumb.

Jacob W P Potuijt, Robert-Jan H Galjaard, Peter J van der Spek, Christianne A van Nieuwenhoven, Nadav Ahituv, Kerby C Oberg, Steven E R Hovius

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of hand surgery, European volume, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Ulnar dimelia - a review of 24 cases.The Journal of hand surgery, European volume · 2023
    Review
  2. Surgical Reconstruction for the Triphalangeal Thumb.Plastic and reconstructive surgery. Global open · 2023
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jacob W P Potuijt1 Department of Plastic and Reconstructive Surgery and Hand Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Robert-Jan H Galjaard2 Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Peter J van der Spek3 Department of Bioinformatics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Christianne A van Nieuwenhoven1 Department of Plastic and Reconstructive Surgery and Hand Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Nadav Ahituv5 Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, SF, USA.
Kerby C Oberg7 Department of Pathology and Human Anatomy, Loma Linda University, Loma Linda, USA.
Steven E R Hovius1 Department of Plastic and Reconstructive Surgery and Hand Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite being a rare congenital limb anomaly, triphalangeal thumb is a subject of research in various scientific fields, providing new insights in clinical research and evolutionary biology. The findings of triphalangeal thumb can be predictive for other congenital anomalies as part of an underlying syndrome. Furthermore, triphalangeal thumb is still being used as a model in molecular genetics to study gene regulation by long-range regulatory elements. We present a review that summarizes a number of scientifically relevant topics that involve the triphalangeal thumb phenotype. Future initiatives involving multidisciplinary teams collaborating in the field of triphalangeal thumb research can lead to a better understanding of the pathogenesis and molecular mechanisms of this condition as well as other congenital upper limb anomalies.

Indexed as

Abnormalities, MultipleFingersGene DuplicationHand Deformities, CongenitalHedgehog ProteinsHumansNerve Tissue ProteinsPhenotypePoint MutationThumbZinc Finger Protein Gli3GLI3 protein, humanHedgehog ProteinsNerve Tissue ProteinsSHH protein, humanZinc Finger Protein Gli3congenital limb deformitiesgenetic enhancer elementshedgehog proteinpolydactylyTriphalangeal thumb

Identifiers

PMID30318985
PMCPMC6297887

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.