Evidence map›Paper›PMID 30318853›Full record

ArticlePhysiological reports2018

Stress-induced modulation of volume-regulated anions channels in human alveolar carcinoma cells.

Martin D Bach, Belinda H Sørensen, Ian H Lambert

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Apoptotic volume decrease (AVD) in AFrontiers in physiology · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Martin D BachSection of Cell Biology and Physiology, Department of Biology, University of Copenhagen, Copenhagen Ø, Denmark.
Belinda H SørensenSection of Cell Biology and Physiology, Department of Biology, University of Copenhagen, Copenhagen Ø, Denmark.
Ian H LambertSection of Cell Biology and Physiology, Department of Biology, University of Copenhagen, Copenhagen Ø, Denmark.
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shift in the cellular homeostasis of the organic osmolyte taurine has been associated with dysregulation of the volume-regulated anion channel (VRAC) complex, which comprises leucine-rich repeat-containing family 8 members (LRRC8A-E). Using SDS-PAGE, western blotting, qRT-PCR, and tracer technique ([

Indexed as

A549 CellsAdenocarcinoma, Bronchiolo-AlveolarCisplatinHEK293 CellsHumansMembrane ProteinsOxidative StressVoltage-Dependent Anion ChannelsCisplatinLRRC8A protein, humanMembrane ProteinsVoltage-Dependent Anion ChannelsAktcisplatinLRRC8AmTORC2p53reactive oxygen species

Identifiers

PMID30318853
PMCPMC6186816
OpenAlexW2896370763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.